1. Gene
  2. IER5 - immediate early response 5 Gene

IER5 - immediate early response 5 Gene

中文名称:立即早期反应 5

种属: Homo sapiens

同用名: SBBI48

基因 ID: 51278 | 基因类型: protein coding

关于 IER5

Cytogenetic location: 1q25.3 Genomic coordinates (GRCh38): 1:181,088,700-181,092,900 (from NCBI)

This gene has 1 transcript (splice variant), 116 orthologues and 2 paralogues.

功能概要

该基因编码的蛋白质类似于其他即时早期反应蛋白质。在小鼠中,一个相似的基因可能在介导细胞对促有丝分裂信号的反应中发挥重要作用。对老鼠的研究发现,清醒和睡眠剥夺后,类似基因的表达会增加。[RefSeq 提供,2008 年 7 月]

This gene encodes a protein that is similar to Other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation. [provided by RefSeq, Jul 2008]

IER5 基因产物(1)

mRNA Protein Name
NM_016545.5 NP_057629.2 immediate early response gene 5 protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
26496226 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
26496226 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25816751 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to heat IDA
IDA: 通过直接分析推断
25816751 GOA
involved in positive regulation of cellular response to heat IMP
IMP: 通过突变表型推断
26496226 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
25816751 GOA
involved in regulation of cell population proliferation IMP
IMP: 通过突变表型推断
26496226 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
25816751 GOA
located in nucleus IDA
IDA: 通过直接分析推断
25816751 GOA
part of protein phosphatase type 2A complex IDA
IDA: 通过直接分析推断
25816751 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

IER5 蛋白结构

IER

IER: Immediate early response protein (IER) (1 - 327)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
蛋白主名 其他名称

immediate early response gene 5 protein

IER5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
IER5 Q5VY09 MINK1 Homo sapiens Q8N4C8-4 26496226
种属内
IER5 Q5VY09 PPP2CA Homo sapiens P67775 26496226
种属内
IER5 Q5VY09 HSF1 Homo sapiens Q00613 26496226
种属内
IER5 Q5VY09 IER5 Homo sapiens Q5VY09 26496226
种属内
IER5 Q5VY09 RPS6KB1 Homo sapiens P23443 26496226
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Bos taurus IER5 VGNC VGNC:30040
Macaca mulatta IER5 VGNC VGNC:73561
Mus musculus IER5 MGD MGI:1337072
Rattus norvegicus IER5 RGD RGD:69252
Felis catus IER5 VGNC VGNC:107880
Canis familiaris IER5 VGNC VGNC:55742