2. Gene
  3. RASL12 - RAS like family 12 Gene

RASL12 - RAS like family 12 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：RAS 样家族 12

种属: Homo sapiens

同用名: RIS

基因 ID: 51285 | 基因类型: protein coding

关于 RASL12

This gene has 3 transcripts (splice variants), 183 orthologues and 35 paralogues. Broad expression in prostate (RPKM 19.4), endometrium (RPKM 17.1) and 21 other tissues.

功能概要

预测启用 GDP 绑定活动； GTP 结合活性；和 GTPase 活性。预计参与信号转导。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RASL12 基因产物(3)

mRNA Protein Name
NM_001307930.2 NP_001294859.1 ras-like protein family member 12 isoform 2
NM_001379429.1 NP_001366358.1 ras-like protein family member 12 isoform 3
NM_016563.4 NP_057647.1 ras-like protein family member 12 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RASL12 蛋白结构

Ras

Ras: Ras family (23 - 184)

  • 0
  • 100
  • 200
  • 266 a.a.
蛋白主名 其他名称

ras-like protein family member 12

Ras family member Ris

RASL12 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RASL12 Q9NYN1 FHL2 Homo sapiens Q14192
Anti Tag CoIP
33961781
种属内
RASL12 Q9NYN1 FHL2 Homo sapiens Q14192
Anti Tag CoIP
28514442
种属内
RASL12 Q9NYN1 FHL3 Homo sapiens Q13643
Y2H Array
32296183
种属内
RASL12 Q9NYN1 FHL3 Homo sapiens Q13643
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Bile Acid Malabsorption, Primary, 2

PBAM2
Diarrhea

Diarrhoea

Diarrhea Of Presumed Infectious Origin
Cholestasis

Obstruction Of Bile Duct

Bile Duct Obstruction

Bile Occlusion

Extrahepatic Biliary Obstruction

Extrahepatic Bile Duct Obstruction

Bile Stasis

Biliary Stasis

Obstructive Hyperbilirubinemia

Obstructed Jaundice

Bile Duct Obstructed

Bile Ductal Obstruction

Biliary Duct Obstruction

Obstructed Bile Ductal

Obstructed Biliary Duct

Obstructed Biliary Ductal

Jaundice Regurgitation

Obstructive Jaundice

Cholestatic Jaundice

Cholestatic Jaundice Syndrome
Acrofacial Dysostosis 1, Nager Type

Nager Syndrome

Nager Acrofacial Dysostosis

AFD1

Preaxial Acrofacial Dysostosis

Mandibulofacial Dysostosis, Treacher Collins Type, With Limb Anomalies

Afd, Nager Type

Nager Acrofacial Dysostosis Syndrome

Nafd

Acrofacial Dysostosis, Nager Type

Afd

Preaxial Manibulofacial Dysostosis

Split Hand Deformity-Mandibulofacial Dysostosis

Preaxial Mandibulofacial Dysostosis

Mandibulofacial Dysostosis With Preaxial Limb Anomalies

Preaxial Acrodysostosis

Afd Nager Type

Mandibulofacial Dysostosis Treacher Collins Type With Limb Anomalies
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11700 RASL12 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus RASL12 VGNC VGNC:64506
Rattus norvegicus RASL12 RGD RGD:1306268
Canis familiaris RASL12 VGNC VGNC:58328
Mus musculus RASL12 MGD MGI:1918034
Macaca mulatta RASL12 VGNC VGNC:76573
Bos taurus RASL12 VGNC VGNC:33756
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