1. Gene
  2. COMMD10 - COMM domain containing 10 Gene

COMMD10 - COMM domain containing 10 Gene

中文名称:含 COMM 域 10

种属: Homo sapiens

同用名: PTD002

基因 ID: 51397 | 基因类型: protein coding

关于 COMMD10

Cytogenetic location: 5q23.1 Genomic coordinates (GRCh38): 5:116,085,025-116,293,287 (from NCBI)

This gene has 7 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in thyroid (RPKM 1.4), adrenal (RPKM 1.3) and 25 other tissues.

功能概要

位于核质中。 [由基因组资源联盟提供,2022 年 4 月]

Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

COMMD10 基因产物(2)

mRNA Protein Name
NM_001308080.2 NP_001295009.1 COMM domain-containing protein 10 isoform b
NM_016144.4 NP_057228.1 COMM domain-containing protein 10 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15799966 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

COMMD10 蛋白结构

COMM_domain

COMM_domain: COMM domain (20 - 201)

  • 0
  • 100
  • 202 a.a.
蛋白主名 其他名称

COMM domain-containing protein 10

COMMD10 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra COMMD10 Q9Y6G5 FKBP1A Homo sapiens Q0VDC6
Validated Y2H
32814053
Intra COMMD10 Q9Y6G5 FKBP1A Homo sapiens Q0VDC6
Y2H Array
32814053
Intra COMMD10 Q9Y6G5 FKBP1A Homo sapiens Q0VDC6
Y2H Pooling
32814053
Intra COMMD10 Q9Y6G5 UQCRC1 Homo sapiens P31930
Validated Y2H
32814053
Intra COMMD10 Q9Y6G5 UQCRC1 Homo sapiens P31930
Y2H Array
32814053
Intra COMMD10 Q9Y6G5 UQCRC1 Homo sapiens P31930
Y2H Pooling
32814053
Intra COMMD10 Q9Y6G5 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
28514442
Intra COMMD10 Q9Y6G5 CCDC93 Homo sapiens Q567U6
Pull Down
25355947
Intra COMMD10 Q9Y6G5 CCDC93 Homo sapiens Q567U6
Anti Tag CoIP
33961781
Intra COMMD10 Q9Y6G5 COMMD5 Homo sapiens Q9GZQ3
Anti Tag CoIP
37172566
Intra COMMD10 Q9Y6G5 COMMD5 Homo sapiens Q9GZQ3
Anti Tag CoIP
33961781
Intra COMMD10 Q9Y6G5 COMMD5 Homo sapiens Q9GZQ3
Anti Tag CoIP
28514442
Intra COMMD10 Q9Y6G5 COMMD5 Homo sapiens Q9GZQ3
TAP
23563313
Intra COMMD10 Q9Y6G5 GATM Homo sapiens P50440
Validated Y2H
32814053
Intra COMMD10 Q9Y6G5 GATM Homo sapiens P50440
Y2H Array
32814053
Intra COMMD10 Q9Y6G5 GATM Homo sapiens P50440
Y2H Pooling
32814053
Intra COMMD10 Q9Y6G5 CCDC22 Homo sapiens O60826
Pull Down
23563313
Intra COMMD10 Q9Y6G5 CCDC22 Homo sapiens O60826
TAP
23563313
Intra COMMD10 Q9Y6G5 CCDC22 Homo sapiens O60826
Anti Tag CoIP
33961781
Intra COMMD10 Q9Y6G5 CCDC22 Homo sapiens O60826
Anti Tag CoIP
28514442
Intra COMMD10 Q9Y6G5 CCDC22 Homo sapiens O60826
Anti Bait CoIP
23563313
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Nephrotic Syndrome, Type 20

NPHS20

Nephrotic Syndrome Type 20

Nephrotic Syndrome 20

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris COMMD10 VGNC VGNC:39492
Macaca mulatta COMMD10 VGNC VGNC:71374
Bos taurus COMMD10 VGNC VGNC:27582
Rattus norvegicus COMMD10 RGD RGD:1303015
Felis catus COMMD10 VGNC VGNC:61075
Mus musculus COMMD10 MGD MGI:1916706