ATP5MC1 - ATP synthase membrane subunit c locus 1 Gene

中文名称：ATP 合成酶膜亚基 c 位点 1

种属: Homo sapiens

同用名: ATP5A; ATP5G; ATP5G1

关于 ATP5MC1

功能概要

该基因编码线粒体 ATP 合酶的一个亚基。线粒体 ATP 合酶催化 ATP 合成，利用氧化磷酸化过程中跨内膜的质子电化学梯度。 ATP 合酶由两个连接的多亚基复合物组成：可溶性催化核心 F1 和跨膜成分 Fo，构成质子通道。线粒体 ATP 合酶的催化部分由 5 个不同的亚基 (alpha、beta、gamma、delta 和 epsilon) 组成，其化学计量为 3 个 alpha、3 个 beta 和其他 3 个的单一代表。质子通道似乎具有九个亚基 (a、b、c、d、e、f、g、F6 和 8) 。该基因是编码质子通道 c 亚基的三个基因之一。这三个基因中的每一个都有不同的线粒体输入序列，但编码相同的成熟蛋白质。已经鉴定出编码相同蛋白质的可变剪接转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a subunit of mitochondrial ATP Synthase. Mitochondrial ATP Synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during Oxidative Phosphorylation. ATP Synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP Synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]