TRMT6 - tRNA methyltransferase 6 non-catalytic subunit Gene

中文名称：tRNA 甲基转移酶 6 非催化亚基

种属: Homo sapiens

同用名: GCD10; CGI-09; Gcd10p

关于 TRMT6

功能概要

该基因编码 tRNA 甲基转移酶 6 蛋白家族的成员。酵母中的一种类似蛋白质是双组分甲基转移酶的一部分，它参与翻译后修饰，在 tRNA 中产生修饰的核苷 1-甲基腺苷。修饰的 1-甲基腺苷会影响引发剂甲硫氨酸的稳定性，并可能参与人类免疫缺陷病毒 1 型的复制。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]