2. Gene
  3. KLF13 - KLF transcription factor 13 Gene

KLF13 - KLF transcription factor 13 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：KLF 转录因子 13

种属: Homo sapiens

同用名: BTEB3; FKLF2; NSLP1; RFLAT1; RFLAT-1

基因 ID: 51621 | 基因类型: protein coding

关于 KLF13

Cytogenetic location: 15q13.3 Genomic coordinates (GRCh38): 15:31,326,835-31,435,665 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 118 orthologues, 22 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 34.5), lung (RPKM 27.2) and 24 other tissues.

功能概要

KLF13 属于包含 3 个经典锌指 DNA 结合结构域的转录因子家族，该结构域由由 2 个半胱氨酸和 2 个组氨酸 (C2H2 基序) 四面体配位的锌原子组成。这些转录因子与富含 GC 的序列和相关的 GT 和 CACCC 盒结合 (Scohy 等人，2000 [PubMed 11087666]) 。[OMIM 提供，2008 年 3 月]

KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]

KLF13 基因产物(2)

mRNA Protein Name
NM_001302461.2 NP_001289390.1 Krueppel-like factor 13 isoform 2
NM_015995.4 NP_057079.2 Krueppel-like factor 13 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17053787 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KLF13 蛋白结构

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (183 - 209)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (214 - 236)

  • 0
  • 100
  • 200
  • 288 a.a.
蛋白主名 其他名称

Krueppel-like factor 13

BTE-binding protein 3

关联疾病

疾病名称 别名
Chromosome 15q13.3 Deletion Syndrome

Chromosome 15q13.3 Microdeletion Syndrome

15q13.3 Microdeletion Syndrome

15q13.3 Microdeletion

Microdeletion 15q13.3 Syndrome

Del(15)(Q13.3)

Monosomy 15q13.3
Tricuspid Valve Stenosis

Tricuspid Stenosis

Tricuspid Stricture

Tricuspid Valve Stricture

Tricuspid Insufficiency With Obstruction

Tricuspid Insufficiency With Stenosis
Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Heart Malformation

Congenital Anomaly Of Heart

Heart Defect

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07334 KLF13 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus KLF13 RGD RGD:1565099
Bos taurus KLF13 VGNC VGNC:106796
Mus musculus KLF13 MGD MGI:1354948
Macaca mulatta KLF13 VGNC VGNC:84365
Felis catus KLF13 VGNC VGNC:80941
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