2. Gene
  3. DHRS7 - dehydrogenase/reductase 7 Gene

DHRS7 - dehydrogenase/reductase 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：脱氢酶/还原酶 7

种属: Homo sapiens

同用名: CGI-86; SDR34C1; retDSR4; retSDR4

基因 ID: 51635 | 基因类型: protein coding

关于 DHRS7

Cytogenetic location: 14q23.1 Genomic coordinates (GRCh38): 14:60,144,119-60,169,889 (from NCBI)

This gene has 11 transcripts (splice variants), 252 orthologues and 13 paralogues. Broad expression in prostate (RPKM 116.8), small intestine (RPKM 40.2) and 22 other tissues.

功能概要

该基因编码短链脱氢酶/还原酶 (SDR) 家族的成员，该家族拥有超过 46,000 名成员。这个家族的成员是代谢许多不同化合物的酶，例如类固醇激素、前列腺素、类维生素 A、脂质和异生素。[RefSeq 提供，2016 年 4 月]

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are Enzymes that metabolize many different compounds, such as steroid Hormones, prostaglandins, retinoids, lipids and xenobiotics. [provided by RefSeq, Apr 2016]

DHRS7 基因产物(4)

mRNA Protein Name
NM_001322280.2 NP_001309209.1 dehydrogenase/reductase SDR family member 7 isoform 2
NM_001322281.2 NP_001309210.1 dehydrogenase/reductase SDR family member 7 isoform 3
NM_001322282.2 NP_001309211.1 dehydrogenase/reductase SDR family member 7 isoform 4 precursor
NM_016029.4 NP_057113.1 dehydrogenase/reductase SDR family member 7 isoform 1 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables all-trans-retinol dehydrogenase (NADP+) activity IDA
IDA: 通过直接分析推断
26466768 GOA
enables carbonyl reductase (NADPH) activity IDA
IDA: 通过直接分析推断
24246760 GOA
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IDA
IDA: 通过直接分析推断
24246760 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
24246760 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DHRS7 蛋白结构

adh_short

adh_short: short chain dehydrogenase (52 - 221)

  • 0
  • 100
  • 200
  • 300
  • 339 a.a.
蛋白主名 其他名称

dehydrogenase/reductase SDR family member 7

dehydrogenase/reductase (SDR family) member 7

DHRS7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra DHRS7 Q9Y394 TMEM120A Homo sapiens Q9BXJ8
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03743 DHRS7 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS03744 DHRS7B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus DHRS7 RGD RGD:1565002
Canis familiaris DHRS7 VGNC VGNC:39935
Bos taurus DHRS7 VGNC VGNC:28043
Felis catus DHRS7 VGNC VGNC:61471
Macaca mulatta DHRS7 VGNC VGNC:71690
Mus musculus DHRS7 MGD MGI:1913625
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