NUDT9 - nudix hydrolase 9 Gene

中文名称：nudix 水解酶 9

种属: Homo sapiens

同用名: NUDT10

关于 NUDT9

功能概要

该基因编码的蛋白质属于 Nudix 水解酶家族。 Nudix 盒存在于催化核苷二磷酸衍生物水解的多种酶家族中。该酶是一种 ADP 核糖焦磷酸酶，可催化 ADP 核糖水解为 AMP 和核糖 5-P。它需要二价金属离子和完整的 Nudix 基序来实现酶活性。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 10 月]

The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse Enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This Enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]