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  2. Rgs8 - regulator of G-protein signaling 8 Gene

Rgs8 - regulator of G-protein signaling 8 Gene

中文名称:G 蛋白信号调节器 8

种属: Rattus norvegicus

基因 ID: 54297 | 基因类型: protein coding

关于 Rgs8

Primary_assembly 13: 65,804,797-65,846,807 forward strand.mRatBN7.2:CM026986.1

This gene has 3 transcripts (splice variants), 199 orthologues, 22 paralogues and is associated with 5 phenotypes. Restricted expression toward (RPKM 151.5).

功能概要

该基因编码的蛋白可启动 G 蛋白 α 亚基结合活性和 GTP 酶激活剂活性。参与多个过程,包括G蛋白偶联的乙酰胆碱受体信号通路; GTP酶活性的正调节;和对苯丙胺的反应。位于树突中;神经细胞体膜;和核。是质膜细胞质侧的外在成分。与人类 RGS8(G 蛋白信号转导 8 的调节因子)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables G-protein alpha-subunit binding activity and GTPase activator activity. Involved in several processes, including G protein-coupled acetylcholine receptor signaling pathway; positive regulation of GTPase activity; and response to amphetamine. Located in dendrite; neuronal cell body membrane; and nucleus. Is extrinsic component of cytoplasmic side of plasma membrane. Orthologous to human RGS8 (regulator of G protein signaling 8). [provided by Alliance of Genome Resources, Apr 2022]

Rgs8 基因产物(1)

mRNA Protein Name
NM_019344.3 NP_062217.1 regulator of G-protein signaling 8
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G-protein alpha-subunit binding IPI
IPI: 通过物理相互作用推断
9394004 RGD
enables GTPase activator activity IDA
IDA: 通过直接分析推断
9394004 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled acetylcholine receptor signaling pathway IDA
IDA: 通过直接分析推断
9394004 RGD
involved in positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
9394004 RGD
involved in regulation of dopamine receptor signaling pathway IDA
IDA: 通过直接分析推断
9394004 RGD
involved in response to amphetamine IEP
IEP: 通过表达模式推断
26321241 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic side of plasma membrane IDA
IDA: 通过直接分析推断
12880183 RGD
located in dendrite IDA
IDA: 通过直接分析推断
12880183 RGD
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
12880183 RGD
located in nucleus IDA
IDA: 通过直接分析推断
12880183 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Rgs8 蛋白结构

RGS_RGS8

RGS_RGS8: cd08711 (97 - 221)

  • 0
  • 100
  • 200
  • 232 a.a.
蛋白主名 其他名称

regulator of G-protein signaling 8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rgs8 NCBI NCBI:85397