1. Gene
  2. GNG2 - G protein subunit gamma 2 Gene

GNG2 - G protein subunit gamma 2 Gene

中文名称:G 蛋白亚基γ2

种属: Homo sapiens

同用名: HG3F1

基因 ID: 54331 | 基因类型: protein coding

关于 GNG2

Cytogenetic location: 14q22.1 Genomic coordinates (GRCh38): 14:51,826,174-51,969,795 (from NCBI)

This gene has 16 transcripts (splice variants), 188 orthologues and 11 paralogues. Broad expression in brain (RPKM 43.3), spleen (RPKM 22.6) and 23 other tissues.

功能概要

该基因编码鸟嘌呤核苷酸结合蛋白的一个γ亚基。这些蛋白质参与跨膜信号机制。各种亚基形成异二聚体,然后与不同的信号分子相互作用。[RefSeq 提供,2011 年 8 月]

This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules. [provided by RefSeq, Aug 2011]

GNG2 基因产物(7)

mRNA Protein Name
NM_001243773.2 NP_001230702.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001243774.2 NP_001230703.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001389707.1 NP_001376636.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001389708.1 NP_001376637.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001389709.1 NP_001376638.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001389710.1 NP_001376639.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_053064.5 NP_444292.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G-protein beta-subunit binding IPI
IPI: 通过物理相互作用推断
12606627 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
23739333 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of heterotrimeric G-protein complex IDA
IDA: 通过直接分析推断
29925951 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GNG2 蛋白结构

G-gamma

G-gamma: GGL domain (7 - 71)

  • 0
  • 71 a.a.
蛋白主名 其他名称

guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

g gamma-I

GNG2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra GNG2 P59768 GNB1 Homo sapiens P62873
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GNG2 RGD RGD:69268
Mus musculus GNG2 MGD MGI:102705
Canis familiaris GNG2 VGNC VGNC:53494
Bos taurus GNG2 VGNC VGNC:29465
Others GNG2 NCBI