SLC38A2 - solute carrier family 38 member 2 Gene

中文名称：溶质载体家族 38 成员 2

种属: Homo sapiens

同用名: ATA2; SAT2; SNAT2; PRO1068

基因 ID: 54407 | 基因类型: protein coding

关于 SLC38A2

Cytogenetic location: 12q13.11 Genomic coordinates (GRCh38): 12:46,358,188-46,372,773 (from NCBI)

This gene has 14 transcripts (splice variants), 260 orthologues and 15 paralogues. Ubiquitous expression in skin (RPKM 105.3), liver (RPKM 101.3) and 25 other tissues.

功能概要

启用中性氨基酸：钠同向转运体活性。参与多个过程，包括氨基酸转运；亚砷酸盐 (3-) 的细胞反应；和 RNA 剪接的正调控。位于细胞质和质膜中。 [由基因组资源联盟提供，2022 年 4 月]

Enables neutral amino acid:sodium symporter activity. Involved in several processes, including amino acid transport; cellular response to arsenite(3-); and positive regulation of RNA splicing. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC38A2 基因产物(2)

mRNA	Protein	Name
NM_001307936.2	NP_001294865.1	sodium-coupled neutral amino acid symporter 2 isoform 2 precursor
NM_018976.5	NP_061849.2	sodium-coupled neutral amino acid symporter 2 isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables amino acid transmembrane transporter activity	IDA IDA: 通过直接分析推断	16621798	GOA
enables amino acid transmembrane transporter activity	IMP IMP: 通过突变表型推断	15922329	GOA
enables amino acid:sodium symporter activity	IDA IDA: 通过直接分析推断	15774260	GOA
enables neutral L-amino acid:sodium symporter activity	IDA IDA: 通过直接分析推断	10930503	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	25759021	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in amino acid transmembrane transport	IMP IMP: 通过突变表型推断	10930503	GOA
involved in amino acid transport	IDA IDA: 通过直接分析推断	15774260	GOA
involved in amino acid transport	IMP IMP: 通过突变表型推断	15922329	GOA
involved in cellular response to arsenite(3-)	IMP IMP: 通过突变表型推断	22215663	GOA
involved in neutral amino acid transport	IDA IDA: 通过直接分析推断	10930503	GOA
involved in positive regulation of RNA splicing	IPI IPI: 通过物理相互作用推断	22215663	GOA
involved in positive regulation of gene expression	IPI IPI: 通过物理相互作用推断	22215663	GOA
involved in regulation of cellular response to stress	IMP IMP: 通过突变表型推断	22215663	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	15581851	GOA
located in plasma membrane	IDA IDA: 通过直接分析推断	15581851	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC38A2 蛋白结构

Aa_trans

0
100
200
300
400
506 a.a.

蛋白主名

其他名称

sodium-coupled neutral amino acid symporter 2

sodium-coupled neutral amino acid transporter 2

amino acid transporter 2

SLC38A2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	SLC38A2	Q96QD8	DCDC2	Homo sapiens	Q9UHG0	Y2H Array	32296183
种属内	SLC38A2	Q96QD8	DCDC2	Homo sapiens	Q9UHG0	Y2H Prey Pooling	32296183
种属内	SLC38A2	Q96QD8	DCDC2	Homo sapiens	Q9UHG0	Validated Y2H	32296183
种属内	SLC38A2	Q96QD8	TMEM237	Homo sapiens	Q96Q45-2	Y2H Prey Pooling	32296183
种属内	SLC38A2	Q96QD8	TMEM237	Homo sapiens	Q96Q45-2	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Adult Syndrome

Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome	Acro Dermato Ungual Lacrimal Tooth Syndrome
Pigment Anomaly-Ectrodactyly-Hypodontia Syndrome	Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome
Adult

Hartnup Disorder

Hartnup Disease	HND
Neutral 1 Amino Acid Transport Defect	Neutral Amino Acid Transport Defect
Deficiency Of Tryptophan Oxygenase	Hartnup'S Disease
Aminoaciduria, Hartnup Type	Disorder Of Neutral Amino Acid Transport

Persistent Fetal Circulation Syndrome

Persistent Fetal Circulation	Fetal Circulation
Persistent Pulmonary Hypertension Of The Newborn	Congenital Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins
Persistent Foetal Circulation	Persistent Foetal Circulation Syndrome
Pfc - [Persistent Fetal Circulation] Syndrome	Pphn - [Persistent Pulmonary Hypertension Of The Newborn]
Newborn Pulmonary Hypertension	Primary Pulmonary Hypertension Of Newborn

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS13220	SLC38A2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	SLC38A2	RGD	RGD:69420
Bos taurus	SLC38A2	VGNC	VGNC:34849
Canis familiaris	SLC38A2	VGNC	VGNC:46393
Felis catus	SLC38A2	VGNC	VGNC:65345
Macaca mulatta	SLC38A2	VGNC	VGNC:77469
Mus musculus	SLC38A2	MGD	MGI:1915010
Others	SLC38A2	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SLC38A2 - solute carrier family 38 member 2 Gene

关于 SLC38A2

功能概要

SLC38A2 基因产物(2)

SLC38A2 蛋白结构

SLC38A2 蛋白互作信息

关联疾病

直系同源

热门区域

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SLC38A2 - solute carrier family 38 member 2 Gene

关于 SLC38A2

功能概要

SLC38A2 基因产物(2)

SLC38A2 蛋白结构

SLC38A2 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z