2. Gene
  3. Cadm1 - cell adhesion molecule 1 Gene

Cadm1 - cell adhesion molecule 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bl2; ST17; Igsf4; Necl2; RA175; Tslc1; Igsf4a; RA175A; RA175B; RA175C; RA175N; SgIGSF; SynCam; 2900073G06Rik; 3100001I08Rik

基因 ID: 54725 | 基因类型: protein coding

关于 Cadm1

功能概要

Enables PDZ domain binding activity; protein homodimerization activity; and signaling receptor binding activity. Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and synapse organization. Acts upstream of or within bone development; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; and unidimensional cell growth. Located in several cellular components, including basolateral plasma membrane; cell body fiber; and varicosity. Is integral component of postsynaptic membrane. Is active in Schaffer collateral - CA1 synapse. Is integral component of presynaptic membrane. Is expressed in several structures, including nervous system; respiratory system; sensory organ; tooth; and urinary system. Human ortholog(s) of this gene implicated in breast carcinoma and prostate Cancer. Orthologous to human CADM1 (cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Cadm1 基因产物(5)

mRNA Protein Name
NM_001025600.1 NP_001020771.1 cell adhesion molecule 1 isoform d precursor
NM_001310841.1 NP_001297770.1 cell adhesion molecule 1 isoform e precursor
NM_018770.3 NP_061240.3 cell adhesion molecule 1 isoform c precursor
NM_207675.2 NP_997558.2 cell adhesion molecule 1 isoform a precursor
NM_207676.2 NP_997559.1 cell adhesion molecule 1 isoform b precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
12826663 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12202822 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
12826663 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
15811952 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within bone development IMP
IMP: 通过突变表型推断
22876197 MGI
acts upstream of or within calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules IDA
IDA: 通过直接分析推断
12202822 MGI
acts upstream of or within cell adhesion IDA
IDA: 通过直接分析推断
12202822 MGI
involved in cell recognition IDA
IDA: 通过直接分析推断
15811952 MGI
involved in detection of stimulus IDA
IDA: 通过直接分析推断
15811952 MGI
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
12826663 MGI
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
IMP: 通过突变表型推断
24687959 MGI
involved in homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: 通过直接分析推断
12826663 MGI
involved in lymphocyte migration into lymphoid organs IMP
IMP: 通过突变表型推断
24687959 MGI
involved in maintenance of postsynaptic specialization structure IDA
IDA: 通过直接分析推断
21145003 MGI
involved in maintenance of postsynaptic specialization structure IMP
IMP: 通过突变表型推断
21145003 MGI
involved in positive regulation of natural killer cell mediated cytotoxicity IDA
IDA: 通过直接分析推断
15811952 MGI
involved in presynapse assembly IDA
IDA: 通过直接分析推断
12202822 MGI
involved in presynapse assembly IMP
IMP: 通过突变表型推断
12202822 MGI
involved in retrograde trans-synaptic signaling by trans-synaptic protein complex IDA
IDA: 通过直接分析推断
23209303 MGI
involved in retrograde trans-synaptic signaling by trans-synaptic protein complex IMP
IMP: 通过突变表型推断
23209303 MGI
involved in susceptibility to natural killer cell mediated cytotoxicity IDA
IDA: 通过直接分析推断
15811952 MGI
acts upstream of or within synapse assembly IDA
IDA: 通过直接分析推断
12202822 MGI
involved in synapse assembly IDA
IDA: 通过直接分析推断
21145003 MGI
involved in synapse assembly IMP
IMP: 通过突变表型推断
21145003 MGI
involved in synaptic membrane adhesion IDA
IDA: 通过直接分析推断
18003830 MGI
involved in synaptic membrane adhesion IEP
IEP: 通过表达模式推断
18003830 MGI
acts upstream of or within unidimensional cell growth IMP
IMP: 通过突变表型推断
18055550 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
21145003 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
21145003 MGI
located in axon IDA
IDA: 通过直接分析推断
15707673 MGI
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
12826663 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
12826663 MGI
located in dendrite IDA
IDA: 通过直接分析推断
15707673 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
12202822 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
12202822 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15707673 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
26687224 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
26687224 MGI
located in synapse IDA
IDA: 通过直接分析推断
12202822 MGI
located in synaptic vesicle IDA
IDA: 通过直接分析推断
12202822 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cell adhesion molecule 1

NECL-2

TSLC-1

immunoglobulin superfamily member 4

immunoglobulin superfamily member 4A

immunosuperfamily protein Bl2

nectin-like 2

nectin-like protein 2

spermatogenic immunoglobulin superfamily

synaptic cell adhesion molecule

tumor suppressor in

重组 Cadm1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70085 CADM1/IGSF4A Protein, Mouse (HEK293, His) Q8R5M8-1 (Q48-H388) ≥95%
HY-P75598 CADM1/IGSF4A Protein, Mouse (Q8R5M8-2, HEK293, His) Q8R5M8-2 (Q48-H377) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01819 CADM1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cadm1 NCBI NCBI:23705
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