1. Gene
  2. ELP6 - elongator acetyltransferase complex subunit 6 Gene

ELP6 - elongator acetyltransferase complex subunit 6 Gene

中文名称:延伸乙酰转移酶复合亚基 6

种属: Homo sapiens

同用名: C3orf75; TMEM103

基因 ID: 54859 | 基因类型: protein coding

关于 ELP6

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:47,495,640-47,513,712 (from NCBI)

This gene has 15 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in testis (RPKM 3.4), adrenal (RPKM 3.4) and 25 other tissues.

功能概要

预计参与细胞迁移的正调控。位于细胞质和细胞核中。伸长子全酶复合体的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in positive regulation of cell migration. Located in cytosol and nucleus. Part of elongator holoenzyme complex. [provided by Alliance of Genome Resources, Apr 2022]

ELP6 基因产物(2)

mRNA Protein Name
NM_001031703.3 NP_001026873.2 elongator complex protein 6 isoform 1
NM_001363957.1 NP_001350886.1 elongator complex protein 6 isoform 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22854966 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
22645656 GOA
part of elongator holoenzyme complex IDA
IDA: 通过直接分析推断
22854966 GOA
part of elongator holoenzyme complex IPI
IPI: 通过物理相互作用推断
22854966 GOA
located in nucleus IDA
IDA: 通过直接分析推断
22645656 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ELP6 蛋白结构

ELP6

ELP6: Elongation complex protein 6 (1 - 251)

  • 0
  • 100
  • 200
  • 266 a.a.
蛋白主名 其他名称

elongator complex protein 6

UPF0405 protein C3orf75

ELP6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ELP6 Q0PNE2 ELP5 Homo sapiens Q8TE02 33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Lipid Pneumonia

Exogenous Lipoid Pneumonia

Lipoid Pneumonitis

Pneumonia, Lipid

Pneumonia Lipid

Lipoid Pneumonia

Neuropathy, Hereditary Sensory And Autonomic, Type Iii

Familial Dysautonomia

Riley-Day Syndrome

Dysautonomia, Familial

HSAN3

Hsan Iii

Fd

Hereditary Sensory And Autonomic Neuropathy Type Iii

Dys

Hereditary Sensory And Autonomic Neuropathy 3

Riley Day Syndrome

Familial Autonomic Nervous Dysfunction

Hereditary Sensory Autonomic Neuropathy Type Iii

Hsan 3

Hsn 3

Hereditary Sensory Neuropathy Type 3

Hsan Type Iii

Hsn-Iii

Hereditary Sensory And Autonomic Neuropathy Type 3

Neuropathy, Hereditary Sensory And Autonomic, 3

Hsn Iii

Dysautonomia Familial

Neuropathy, Sensory And Autonomic, Hereditary, Type Iii

Hsan3 - [Hereditary Sensory And Autonomic Neuropathy Type 3]

Vasomotor Rhinitis

Rhinitis, Vasomotor

Rhinitis Vasomotor

Vmr - [Vasomotor Rhinitis]

Hereditary Sensory Neuropathy

Hereditary Sensory And Autonomic Neuropathy

Hereditary Sensory And Autonomic Neuropathies

Familial Dysautonomia, Type Ii

Hsan

Sensory Neuropathy Hereditary

Neuropathy, Sensory And Autonomic, Hereditary

Neuropathy, Sensory, Hereditary

Sensory Neuropathy, Hereditary

Charcot-Marie-Tooth Disease

Cmt - [Charcot-Marie-Tooth Disease]

Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy

Benign Rolandic Epilepsy

Epilepsy, Rolandic

Bcects

Benign Childhood Epilepsy With Centrotemporal Spike

Sylvan Seizures

Becrs

Bects

Bre

Benign Epilepsy Of Childhood With Centrotemporal Spikes

Benign Familial Epilepsy Of Childhood With Rolandic Spikes

Centrotemporal Epilepsy

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus ELP6 MGD MGI:1919349
Bos taurus ELP6 VGNC VGNC:28459
Felis catus ELP6 VGNC VGNC:61830
Rattus norvegicus ELP6 RGD RGD:1305478
Macaca mulatta ELP6 VGNC VGNC:72113
Canis familiaris ELP6 VGNC VGNC:49826