1. Gene
  2. ODAM - odontogenic, ameloblast associated Gene

ODAM - odontogenic, ameloblast associated Gene

中文名称:牙源性,成釉细胞相关

种属: Homo sapiens

同用名: APIN

基因 ID: 54959 | 基因类型: protein coding

关于 ODAM

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:70,195,725-70,204,576 (from NCBI)

This gene has 6 transcripts (splice variants) and 89 orthologues. Restricted expression toward salivary gland (RPKM 78.4).

功能概要

参与多个过程,包括 GTPase 活性的正向调节;参与伤口愈合的上皮细胞增殖的正调节;和大分子代谢过程的正向调控。位于多个细胞成分中,包括细胞外空间;有丝分裂纺锤体;和核质。 [由基因组资源联盟提供,2022 年 4 月]

Involved in several processes, including positive regulation of GTPase activity; positive regulation of epithelial cell proliferation involved in wound healing; and positive regulation of macromolecule metabolic process. Located in several cellular components, including extracellular space; mitotic spindle; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ODAM 基因产物(2)

mRNA Protein Name
NM_001385579.1 NP_001372508.1 odontogenic ameloblast-associated protein isoform 2 precursor
NM_017855.4 NP_060325.3 odontogenic ameloblast-associated protein isoform 1 precursor

ODAM 蛋白结构

ODAM

ODAM: Odontogenic ameloblast-associated family (16 - 279)

  • 0
  • 100
  • 200
  • 279 a.a.
蛋白主名 其他名称

odontogenic ameloblast-associated protein

odontogenic, ameloblast asssociated

ODAM 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ODAM A1E959 VENTX Homo sapiens O95231
Validated Y2H
32296183
种属内
ODAM A1E959 ADAM15 Homo sapiens Q13444-2
Validated Y2H
32296183
种属内
ODAM A1E959 SPATA31A7 Homo sapiens Q8IWB4
Validated Y2H
32296183
种属内
ODAM A1E959 MED25 Homo sapiens Q71SY5
Validated Y2H
32296183
种属内
ODAM A1E959 FHL2 Homo sapiens Q14192
Anti Tag CoIP
33961781
种属内
ODAM A1E959 FHL2 Homo sapiens Q14192
Anti Tag CoIP
28514442
种属内
ODAM A1E959 SDCBP Homo sapiens O00560
Validated Y2H
32296183
种属内
ODAM A1E959 HGS Homo sapiens O14964
Validated Y2H
32296183
种属内
ODAM A1E959 SNRPC Homo sapiens P09234
Validated Y2H
32296183
种属内
ODAM A1E959 ARID5A Homo sapiens Q03989
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Amelogenesis Imperfecta, Type Iiia

Ai3

Adhcai

Amelogenesis Imperfecta Type 3

AI3A

Amelogenesis Imperfecta, Type Iii

Amelogenesis Imperfecta, Hypocalcification Type, Autosomal Dominant

Amelogenesis Imperfecta Type 3a

Amelogenesis Imperfecta Hypomineralization Type

Amelogenesis Imperfecta Type Iii

Hypocalcified Amelogenesis Imperfecta

Amelogenesis Imperfecta, Type 3

Amelogenesis Imperfecta, Hypomineralization Type

Autosomal Dominant Amelogenesis Imperfecta Hypocalcification Type

Amelogenesis Imperfecta 3a

Amelogenesis Imperfecta Hypocalcification Type Autosomal Dominant

Bone Benign Neoplasm
Crisponi/Cold-Induced Sweating Syndrome 1

Crisponi Syndrome

Cold-Induced Sweating Syndrome 1

CISS1

Sohar-Crisponi Syndrome

Muscle Contractions, Tetanoform, With Characteristic Face, Camptodactyly, Hyperthermia, And Sudden Death

Muscle Contractions Tetanoform With Characteristic Face Camptodactyly Hyperthermia And Sudden Death

Dental Fluorosis

Mottled Teeth

Intrinsic Enamel Discolouration Of Fluorosis

Mottling Of Enamel

Fluorosis, Dental

Dental Fluorosis, Acquired

Cold-Induced Sweating Syndrome

Crisponi Syndrome

Sohar-Crisponi Syndrome

Ciss

Cntf Receptor-Related Disorders

Muscle Contractions, Tetanoform, With Characteristic Face, Camptodactyly, Hyperthermia, And Sudden Death

Sweating Syndrome, Cold-Induced

Gingival Fibromatosis

Hereditary Gingival Fibromatosis

Hereditary Gingival Hyperplasia

Autosomal Dominant Gingival Fibromatosis

Autosomal Dominant Gingival Hyperplasia

Fibromatosis, Gingival, Hereditary

Fibromatosis, Gingival

Amelogenesis Imperfecta

Ai

Congenital Enamel Hypoplasia

Al - [Amelogenesis Imperfecta]

Tooth Agenesis

Oligodontia

Hypodontia

Selective Tooth Agenesis

Tooth Agenesis, Selective

Familial Tooth Agenesis

Anodontia

Congenital Absence Of One Tooth

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ODAM RGD RGD:1561883
Canis familiaris ODAM VGNC VGNC:44096
Mus musculus ODAM MGD MGI:1916842
Felis catus ODAM VGNC VGNC:63948
Bos taurus ODAM VGNC VGNC:50115