NMRK1 - nicotinamide riboside kinase 1 Gene

中文名称：烟酰胺核苷激酶 1

种属: Homo sapiens

同用名: NRK1; C9orf95; bA235O14.2

关于 NMRK1

功能概要

烟酰胺腺嘌呤二核苷酸 (NAD+) 对于所有生物体的生命都是必不可少的，它既是氧化还原酶的辅酶，又是各种反应中使用的 ADP-核糖基的来源。烟酸和烟酰胺统称为烟酸，是 NAD+的维生素前体。烟酰胺核苷激酶，例如 NRK1，以烟酰胺核苷为前体，通过烟酰胺单核苷酸合成 NAD+ (Bieganowski 和 Brenner，2004 [PubMed 15137942]) 。[OMIM 提供，2008 年 3 月]

Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 [PubMed 15137942]).[supplied by OMIM, Mar 2008]