1. Gene
  2. ETNK2 - ethanolamine kinase 2 Gene

ETNK2 - ethanolamine kinase 2 Gene

中文名称:乙醇胺激酶 2

种属: Homo sapiens

同用名: EKI2; HMFT1716

基因 ID: 55224 | 基因类型: protein coding

关于 ETNK2

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:204,131,062-204,152,044 (from NCBI)

This gene has 11 transcripts (splice variants), 215 orthologues and 3 paralogues. Biased expression in testis (RPKM 38.7), liver (RPKM 35.9) and 9 other tissues.

功能概要

该基因编码的蛋白质是胆碱/乙醇胺激酶家族的成员,该家族通过胞苷二磷酸 (CDP) 乙醇胺途径催化磷脂酰乙醇胺 (PtdEtn) 生物合成的第一步。可变剪接导致多个转录本变体。[RefSeq 提供,2014 年 7 月]

The protein encoded by this gene is a member of choline/ethanolamine kinase family which catalyzes the first step of phosphatidylethanolamine (PtdEtn) biosynthesis via the cytidine diphosphate (CDP) ethanolamine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

ETNK2 基因产物(4)

mRNA Protein Name
NM_001297760.2 NP_001284689.1 ethanolamine kinase 2 isoform 2
NM_001297761.2 NP_001284690.1 ethanolamine kinase 2 isoform 3
NM_001297762.2 NP_001284691.1 ethanolamine kinase 2 isoform 4
NM_018208.4 NP_060678.2 ethanolamine kinase 2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ETNK2 蛋白结构

Choline_kinase

Choline_kinase: Choline/ethanolamine kinase (107 - 300)

  • 0
  • 100
  • 200
  • 300
  • 386 a.a.
蛋白主名 其他名称

ethanolamine kinase 2

ethanolamine kinase-like protein

ETNK2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ETNK2 Q9NVF9 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
种属内
ETNK2 Q9NVF9 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
种属内
ETNK2 Q9NVF9 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
种属内
ETNK2 Q9NVF9 KRTAP12-2 Homo sapiens P59991
Y2H Prey Pooling
32296183
种属内
ETNK2 Q9NVF9 KRTAP12-2 Homo sapiens P59991
Y2H Array
32296183
种属内
ETNK2 Q9NVF9 ATN1 Homo sapiens Q86V38
Y2H Prey Pooling
32296183
种属内
ETNK2 Q9NVF9 ATN1 Homo sapiens Q86V38
Y2H Array
32296183
种属内
ETNK2 Q9NVF9 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
种属内
ETNK2 Q9NVF9 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
种属内
ETNK2 Q9NVF9 HNRNPK Homo sapiens P61978-2
Y2H Prey Pooling
32296183
种属内
ETNK2 Q9NVF9 HNRNPK Homo sapiens P61978-2
Y2H Array
32296183
种属内
ETNK2 Q9NVF9 STX1A Homo sapiens Q16623
Y2H Array
32296183
种属内
ETNK2 Q9NVF9 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Prostate Carcinoma In Situ

Carcinoma In Situ Of Prostate

Grade Iii Pin

Pin Iii

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ETNK2 RGD RGD:1305304
Canis familiaris ETNK2 VGNC VGNC:40493
Mus musculus ETNK2 MGD MGI:2443760
Macaca mulatta ETNK2 VGNC VGNC:72353
Felis catus ETNK2 VGNC VGNC:61979
Bos taurus ETNK2 VGNC VGNC:28625