1. Gene
  2. TRAPPC14 - trafficking protein particle complex subunit 14 Gene

TRAPPC14 - trafficking protein particle complex subunit 14 Gene

种属: Homo sapiens (human)

同用名: MAP11; MCPH25; C7orf43

基因 ID: 55262 | 基因类型: protein coding

关于 TRAPPC14

功能概要

Enables alpha-tubulin binding activity. Involved in cilium assembly and regulation of cell population proliferation. Located in several cellular components, including microtubule cytoskeleton; midbody; and plasma membrane. Part of TRAPPII protein complex. Implicated in primary autosomal recessive microcephaly. [provided by Alliance of Genome Resources, Apr 2022]

TRAPPC14 基因产物(1)

mRNA Protein Name
NM_018275.5 NP_060745.3 trafficking protein particle complex subunit 14 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-tubulin binding IDA
IDA: 通过直接分析推断
30715179 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
31467083 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cilium assembly IMP
IMP: 通过突变表型推断
31467083 GOA
involved in regulation of cell population proliferation IDA
IDA: 通过直接分析推断
30715179 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of TRAPPII protein complex IMP
IMP: 通过突变表型推断
31467083 GOA
located in midbody IDA
IDA: 通过直接分析推断
30715179 GOA
located in mitotic spindle IDA
IDA: 通过直接分析推断
30715179 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

trafficking protein particle complex subunit 14

microtubule associated protein 11

trafficking protein particle complex 14

uncharacterized protein C7orf43

TRAPPC14 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TRAPPC14 Q8WVR3 KRTAP6-1 Homo sapiens Q3LI64
Y2H Prey Pooling
32296183
种属内
TRAPPC14 Q8WVR3 KRTAP6-1 Homo sapiens Q3LI64
Y2H Array
32296183
种属内
TRAPPC14 Q8WVR3 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
种属内
TRAPPC14 Q8WVR3 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
种属内
TRAPPC14 Q8WVR3 TGM1 Homo sapiens P22735
Y2H Prey Pooling
32296183
种属内
TRAPPC14 Q8WVR3 TGM1 Homo sapiens P22735
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用