2. Gene
  3. PPP3R2 - protein phosphatase 3 regulatory subunit B, beta Gene

PPP3R2 - protein phosphatase 3 regulatory subunit B, beta Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白磷酸酶 3 调节亚基 B，β

种属: Homo sapiens

同用名: PPP3RL

基因 ID: 5535 | 基因类型: protein coding

关于 PPP3R2

Cytogenetic location: 9q31.1 Genomic coordinates (GRCh38): 9:101,591,604-101,594,969 (from NCBI)

This gene has 2 transcripts (splice variants), 32 orthologues and 8 paralogues.

功能概要

预计可启用钙离子结合活性和钙依赖性蛋白丝氨酸/苏氨酸磷酸酶调节剂活性。预计参与催化活性的调节。预计在透明带渗透的上游或渗透内起作用。预测位于精子线粒体鞘内。预计是神经钙蛋白复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium ion binding activity and calcium-dependent protein serine/threonine Phosphatase regulator activity. Predicted to be involved in regulation of catalytic activity. Predicted to act upstream of or within penetration of zona pellucida. Predicted to be located in sperm mitochondrial sheath. Predicted to be part of Calcineurin complex. [provided by Alliance of Genome Resources, Apr 2022]

PPP3R2 基因产物(1)

mRNA Protein Name
NM_147180.4 NP_671709.2 calcineurin subunit B type 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent protein serine/threonine phosphatase regulator activity IDA
IDA: 通过直接分析推断
26429887 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PPP3R2 蛋白结构

EF-hand_7

EF-hand_7: EF-hand domain pair (25 - 79)

EF-hand_7

EF-hand_7: EF-hand domain pair (94 - 158)

  • 0
  • 100
  • 173 a.a.
蛋白主名 其他名称

calcineurin subunit B type 2

CBLP

关联疾病

疾病名称 别名
Cataract 3, Multiple Types

Cataract 3 Multiple Types

CTRCT3

Cca2

Cataract, Congenital, Cerulean Type, 2

Cataract 3, Multiple Types, With Or Without Microcornea

Cataract 3 Multiple Types With Or Without Microcornea

Congenital Cerulean Type Cataract 2

Congenital Cataract Blue Dot Type 2

Congenital Cataract Cerulean Type 2

Cspc

Sutural Cataract With Punctate And Cerulean Opacities
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11027 PPP3R2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus PPP3R2 MGD MGI:107171
Rattus norvegicus PPP3R2 RGD RGD:69232
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