ITLN1 - intelectin 1 Gene

中文名称：智力 1

种属: Homo sapiens

同用名: HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin

基因 ID: 55600 | 基因类型: protein coding

关于 ITLN1

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:160,876,540-160,885,180 (from NCBI)

This gene has 3 transcripts (splice variants), 259 orthologues and 1 paralogue. Biased expression in colon (RPKM 361.8), small intestine (RPKM 202.0) and 3 other tissues.

功能概要

启用钙离子结合活性；相同的蛋白质结合活性；和寡糖结合活性。参与葡萄糖输入的正向调节；蛋白质磷酸化的正调节；和蛋白质同源三聚化。位于细胞外外泌体。受体复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables calcium ion binding activity; identical protein binding activity; and oligosaccharide binding activity. Involved in positive regulation of glucose import; positive regulation of protein phosphorylation; and protein homotrimerization. Located in extracellular exosome. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

ITLN1 基因产物(1)

mRNA	Protein	Name
NM_017625.3	NP_060095.2	intelectin-1 precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables calcium ion binding	IDA IDA: 通过直接分析推断	26148048	GOA
enables identical protein binding	IPI IPI: 通过物理相互作用推断	26148048	GOA
enables oligosaccharide binding	IDA IDA: 通过直接分析推断	26148048	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	26819645	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of D-glucose import	IDA IDA: 通过直接分析推断	16531507	GOA
involved in positive regulation of protein phosphorylation	IDA IDA: 通过直接分析推断	16531507	GOA
involved in protein homotrimerization	IDA IDA: 通过直接分析推断	26148048	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of receptor complex	IDA IDA: 通过直接分析推断	23382219	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

intelectin-1

ITLN-1

ITLN1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	ITLN1	Q8WWA0	DNAJC12	Homo sapiens	Q9UKB3	Anti Tag CoIP	28514442
种属内	ITLN1	Q8WWA0	ITLN2	Homo sapiens	Q8WWU7	Anti Tag CoIP	33961781
种属内	ITLN1	Q8WWA0	HSPA5	Homo sapiens	P11021	Anti Tag CoIP	33961781
种属内	ITLN1	Q8WWA0	DNAJC12	Homo sapiens	Q9UKB3	Anti Tag CoIP	33961781
种属内	ITLN1	Q8WWA0	ITLN1	Homo sapiens	Q8WWA0	Comigration in SDS	26148048
种属内	ITLN1	Q8WWA0	ITLN2	Homo sapiens	Q8WWU7	Anti Tag CoIP	28514442
种属内	ITLN1	Q8WWA0	ENDOG	Homo sapiens	Q14249	Anti Tag CoIP	33961781
种属内	ITLN1	Q8WWA0	NACC1	Homo sapiens	Q96RE7	Anti Tag CoIP	28514442
种属内	ITLN1	Q8WWA0	NACC1	Homo sapiens	Q96RE7	Anti Tag CoIP	33961781
种属内	ITLN1	Q8WWA0	HSPA5	Homo sapiens	P11021	Anti Tag CoIP	28514442
种属内	ITLN1	Q8WWA0	ENDOG	Homo sapiens	Q14249	Anti Tag CoIP	28514442
种属内	ITLN1	Q8WWA0	ITLN1	Homo sapiens	Q8WWA0	X-Ray Diffraction	26148048

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Pleuropneumonia

Type 2 Diabetes Mellitus

Insulin Resistance	NIDDM
Type 2 Diabetes	Diabetes Mellitus, Non-Insulin-Dependent
T2D	Noninsulin-Dependent Diabetes Mellitus
Diabetes Mellitus, Type Ii	Maturity-Onset Diabetes
Insulin Resistance, Severe, Digenic	Diabetes Mellitus, Type 2
Diabetes Mellitus, Noninsulin-Dependent	Diabetes Mellitus, Noninsulin-Dependent, Association With
Diabetes Mellitus, Noninsulin-Dependent, Late Onset	Hypertension, Insulin Resistance-Related, Susceptibility To
Insulin Resistance, Susceptibility To	Non-Insulin-Dependent Diabetes Mellitus
Type Ii Diabetes Mellitus	Adult-Onset Diabetes Mellitus
Maturity-Onset Diabetes Mellitus	Diabetes Mellitus Type 2
Type Ii Diabetes	Type 2 Diabetes Mellitus, Susceptibility To
Diabetes, Type 2	Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To
Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To	Diabetes Mellitus, Type 2, Susceptibility To
Diabetes Mellitus, Noninsulin-Dependent, 2	Diabetes Mellitus, Type Ii, Susceptibility To
Hypertension, Insulin Resistance-Related	Adult-Onset Diabetes
Aodm	Diabetes Mellitus, Adult-Onset
Diabetes Mellitus Type Ii	Diabetes Mellitus Type 2, Susceptibility To
Diabetes, Type Ii, Susceptibility To	Diabetes Type 2
Diabetes Mellitus	Adult Onset Diabetes
Maturity Onset Diabetes	Nonketotic Diabetes
Non-Insulin Dependent Diabetes Mellitus	T2dm - [Type 2 Diabetes Mellitus]
Niddm - [Non Insulin Dependent Diabetes Mellitus]	Dm2
Dm Type Ii	Diabetic Type 2
Insulin Requiring Type 2 Diabetes	Noninsulin Dependent Diabetes
Non-Insulin-Dependent Diabetes Mellitus Without Complications	Diabetes Due To Insulin Secretory Defect
Diabetes Mellitus Due To Insulin Secretory Defect	Non-Insulin-Dependent Diabetes Of The Young
Senile Diabetes	Nonketotic Hyperglycaemia
Stable Diabetes

Body Mass Index Quantitative Trait Locus 11

OBESITY	Obesity, Susceptibility To
Leanness, Inherited	Obesity, Susceptibility To, Bmiq11
Obesity, Mild, Early-Onset	Obesity, Association With
Obesity, Early-Onset, Susceptibility To	Obesity, Severe
Obesity, Severe, And Type Ii Diabetes	Obesity, Late-Onset
Obesity , Susceptibility To	BMIQ11
Obesity Bmiq11	Obesity, Early-Onset
Simple Obesity Nos	Excess Fat
Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified	Adiposis

Nonobstructive Coronary Artery Disease

Non-Cad

Non-Obstructive Coronary Artery Disease

Leptin Deficiency Or Dysfunction

Morbid Obesity	Obesity Due To Congenital Leptin Deficiency
LEPD	Congenital Leptin Deficiency
Obesity, Morbid	Obesity, Morbid, Due To Leptin Deficiency
Severe Obesity	Obesity, Morbid, Nonsyndromic 1
Leptin Deficiency	Obesity, Severe, Due To Leptin Deficiency
Leptin	Morbid Obesity Due To Leptin Deficiency
Obesity Morbid	Leptin Dysfunction

Diabetes Mellitus

Diabetes

Cardiovascular System Disease

Abnormality Of The Cardiovascular System	Cardiovascular Disease
Disease Of Subdivision Of Hemolymphoid System	Disorder Of Cardiovascular System
Cardiovascular Diseases

Osteoporosis

Postmenopausal Osteoporosis	Osteoporosis, Postmenopausal
Bone Mineral Density Quantitative Trait Locus	Bmnd
Osteoporosis, Involutional	Osteoporosis, Susceptibility To
Osteoporosis, Postmenopausal, Susceptibility	Bone Mineral Density Variation Qtl, Osteoporosis
OSTEOP	Involutional Osteoporosis
Senile Osteoporosis	Osteoporosis Postmenopausal
Bone Mineral Density, Quantitative Trait Locus	Osteoporosis, Senile
Idiopathic Osteoporosis	Bone Rarefaction Nos
Type 1 Osteoporosis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06982	ITLN1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	ITLN1	RGD	RGD:1561048
Macaca mulatta	ITLN1	VGNC	VGNC:99984
Mus musculus	ITLN1	MGD	MGI:1333831
Others	ITLN1	NCBI

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

ITLN1 - intelectin 1 Gene

关于 ITLN1

功能概要

ITLN1 基因产物(1)

ITLN1 蛋白互作信息

关联疾病

直系同源

热门区域

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ITLN1 - intelectin 1 Gene

关于 ITLN1

功能概要

ITLN1 基因产物(1)

ITLN1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

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Z