2. Gene
  3. PNRC2 - proline rich nuclear receptor coactivator 2 Gene

PNRC2 - proline rich nuclear receptor coactivator 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：富脯氨酸的核受体共激活因子 2

种属: Homo sapiens

基因 ID: 55629 | 基因类型: protein coding

关于 PNRC2

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:23,959,164-23,963,462 (from NCBI)

This gene has 5 transcripts (splice variants), 198 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 68.8), lymph node (RPKM 67.1) and 25 other tissues.

功能概要

参与核转录的 mRNA 分解代谢过程，无义介导的衰变。位于高尔基体； P 体；和核质。 [由基因组资源联盟提供，2022 年 4 月]

Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in Golgi apparatus; P-body; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PNRC2 基因产物(1)

mRNA Protein Name
NM_017761.4 NP_060231.1 proline-rich nuclear receptor coactivator 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19150429 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IDA
IDA: 通过直接分析推断
19150429 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in P-body IDA
IDA: 通过直接分析推断
19150429 GOA
located in nucleus IDA
IDA: 通过直接分析推断
19150429 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PNRC2 蛋白结构

PNRC

PNRC: Proline-rich nuclear receptor coactivator motif (89 - 138)

  • 0
  • 100
  • 139 a.a.
蛋白主名 其他名称

proline-rich nuclear receptor coactivator 2

PNRC2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra PNRC2 Q9NPJ4 GALK1 Homo sapiens P51570
Y2H Array
32296183
Intra PNRC2 Q9NPJ4 UPF1 Homo sapiens Q92900
Y2H
19150429
Intra PNRC2 Q9NPJ4 UPF1 Homo sapiens Q92900
Anti Tag CoIP
19150429
Intra PNRC2 Q9NPJ4 UPF1 Homo sapiens Q92900
Pull Down
19150429
Intra PNRC2 Q9NPJ4 DCP1A Homo sapiens Q9NPI6
Y2H Array
32296183
Intra PNRC2 Q9NPJ4 DCP1A Homo sapiens Q9NPI6
Y2H Prey Pooling
25416956
Intra PNRC2 Q9NPJ4 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
19150429
Intra PNRC2 Q9NPJ4 DCP1A Homo sapiens Q9NPI6
Y2H Prey Pooling
32296183
Intra PNRC2 Q9NPJ4 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
33961781
Intra PNRC2 Q9NPJ4 DCP1A Homo sapiens Q9NPI6
Y2H Array
31515488
Intra PNRC2 Q9NPJ4 DCP1A Homo sapiens Q9NPI6
Confocal
19150429
Intra PNRC2 Q9NPJ4 DCP1A Homo sapiens Q9NPI6
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Murray Valley Encephalitis

Australian Encephalitis

Australian X Disease

Encephalitis Australia

Murray River Encephalitis

Australian Arboencephalitis

Australian X Disorder

Mve - [Murray Valley Encephalitis]
Holoprosencephaly 3

HPE3

Hlp3

Holoprosencephaly-3

Holoprosencephaly, Type 3
Pancreatic Adenosquamous Carcinoma

Adenosquamous Carcinoma Of Pancreas

Adenosquamous Carcinoma Of The Pancreas
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10803 PNRC2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PNRC2 VGNC VGNC:100042
Rattus norvegicus PNRC2 RGD RGD:1642418
Mus musculus PNRC2 MGD MGI:106512
Felis catus PNRC2 VGNC VGNC:107602
Bos taurus PNRC2 VGNC VGNC:33099
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