1. Gene
  2. CDC37L1 - cell division cycle 37 like 1, HSP90 cochaperone Gene

CDC37L1 - cell division cycle 37 like 1, HSP90 cochaperone Gene

中文名称:细胞分裂周期 37 like 1, HSP90 cochaperone

种属: Homo sapiens

同用名: HARC; CDC37B

基因 ID: 55664 | 基因类型: protein coding

关于 CDC37L1

Cytogenetic location: 9p24.1 Genomic coordinates (GRCh38): 9:4,679,569-4,708,399 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 13.5), heart (RPKM 8.3) and 25 other tissues.

功能概要

CDC37L1 是一种细胞质磷蛋白,与 HSP90 (HSPCA; MIM 140571) 以及其他几种参与 HSP90 介导的蛋白质折叠的蛋白质一起存在 (Scholz 等人,2001 [PubMed 11413142]) 。[OMIM 提供,2008 年 3 月] ]

CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).[supplied by OMIM, Mar 2008]

CDC37L1 基因产物(1)

mRNA Protein Name
NM_017913.4 NP_060383.2 hsp90 co-chaperone Cdc37-like 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21988832 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CDC37L1 蛋白结构

CDC37_M

CDC37_M: Cdc37 Hsp90 binding domain (132 - 282)

  • 0
  • 100
  • 200
  • 300
  • 337 a.a.
蛋白主名 其他名称

hsp90 co-chaperone Cdc37-like 1

CDC37 cell division cycle 37 homolog-like 1

CDC37L1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CDC37L1 Q7L3B6 STIP1 Homo sapiens P31948
Anti Tag CoIP
25036637
Intra CDC37L1 Q7L3B6 HSP90AA1 Homo sapiens P07900
Lumier
25036637
Intra CDC37L1 Q7L3B6 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
25036637
Intra CDC37L1 Q7L3B6 HSP90AB1 Homo sapiens P08238
Y2H Array
25416956
Intra CDC37L1 Q7L3B6 HSP90AB1 Homo sapiens Q6PK50
Lumier
25036637
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Delusional Disorder

Persistent Delusional Disorders

Delusional Perception

Induced Delusional Disorder

Ulceroglandular Tularemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus CDC37L1 VGNC VGNC:27067
Macaca mulatta CDC37L1 VGNC VGNC:70790
Rattus norvegicus CDC37L1 RGD RGD:1309295
Canis familiaris CDC37L1 VGNC VGNC:38995
Mus musculus CDC37L1 MGD MGI:1914322
Felis catus CDC37L1 VGNC VGNC:60655