1. Gene
  2. Cxcl13 - chemokine (C-X-C motif) ligand 13 Gene

Cxcl13 - chemokine (C-X-C motif) ligand 13 Gene

种属: Mus musculus

同用名: BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik

基因 ID: 55985 | 基因类型: protein coding

关于 Cxcl13

功能概要

Enables CXCR5 Chemokine Receptor binding activity and chemokine activity. Involved in several processes, including B cell chemotaxis across high endothelial venule; activation of GTPase activity; and lymph node development. Located in extracellular space. Is expressed in Peyer's patch; aorta; central nervous system; and retina. Orthologous to human CXCL13 (C-X-C motif chemokine ligand 13). [provided by Alliance of Genome Resources, Apr 2022]

Cxcl13 基因产物(1)

mRNA Protein Name
NM_018866.2 NP_061354.1 C-X-C motif chemokine 13 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables CXCR5 chemokine receptor binding IDA
IDA: 通过直接分析推断
9463416 MGI
enables chemokine activity IDA
IDA: 通过直接分析推断
15972452 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell chemotaxis IMP
IMP: 通过突变表型推断
15972452 MGI
involved in B cell chemotaxis across high endothelial venule IDA
IDA: 通过直接分析推断
15972452 MGI
involved in activation of GTPase activity IDA
IDA: 通过直接分析推断
15972452 MGI
involved in lymph node development IDA
IDA: 通过直接分析推断
19783990 MGI
acts upstream of or within lymph node development IMP
IMP: 通过突变表型推断
12732660 MGI
involved in lymphocyte chemotaxis across high endothelial venule IMP
IMP: 通过突变表型推断
15972452 MGI
involved in positive regulation of cell-cell adhesion mediated by integrin IDA
IDA: 通过直接分析推断
15972452 MGI
involved in positive regulation of integrin activation IDA
IDA: 通过直接分析推断
15972452 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
23460747 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

C-X-C motif chemokine 13

B lymphocyte chemoattractant

CXC chemokine BLC

small inducible cytokine subfamily B (Cys-X-Cys), member 13

small-inducible cytokine B13

重组 Cxcl13 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77911 BCA-1/CXCL13 Protein, Mouse (HEK293, His) O55038 (I22-A109) ≥95%
HY-P77912 BCA-1/CXCL13 Protein, Mouse (HEK293, Fc) O55038 (I22-A109) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cxcl13 NCBI NCBI:10563
Macaca fascicularis Cxcl13 NCBI NCBI:102123271
Susscrofa domestica Cxcl13 NCBI
Rattus norvegicus Cxcl13 NCBI NCBI:498335