2. Gene
  3. TEX14 - testis expressed 14, intercellular bridge forming factor Gene

TEX14 - testis expressed 14, intercellular bridge forming factor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：睾丸表达 14，细胞间桥形成因子

种属: Homo sapiens

同用名: CT113; SPGF23

基因 ID: 56155 | 基因类型: protein coding

关于 TEX14

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:58,556,678-58,692,045 (from NCBI)

This gene has 6 transcripts (splice variants), 129 orthologues and is associated with 2 phenotypes. Restricted expression toward testis (RPKM 18.9).

功能概要

由该基因编码的蛋白质是精子发生所需的生殖细胞细胞间桥所必需的。已发现该基因编码不同亚型的三种转录变体。[RefSeq 提供，2011 年 1 月]

The protein encoded by this gene is necessary for intercellular bridges in germ cells, which are required for spermatogenesis. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]

TEX14 基因产物(3)

mRNA Protein Name
NM_001201457.2 NP_001188386.1 inactive serine/threonine-protein kinase TEX14 isoform c
NM_031272.5 NP_112562.3 inactive serine/threonine-protein kinase TEX14 isoform b
NM_198393.4 NP_938207.2 inactive serine/threonine-protein kinase TEX14 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20176808 GOA
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
22405274 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TEX14 蛋白结构

Ank_2

Ank_2: Ankyrin repeats (3 copies) (27 - 118)

Pkinase_Tyr

Pkinase_Tyr: Protein tyrosine kinase (289 - 500)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1497 a.a.
蛋白主名 其他名称

inactive serine/threonine-protein kinase TEX14

cancer/testis antigen 113

TEX14 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TEX14 Q8IWB6 LHX3 Homo sapiens Q9UBR4-2
Y2H Prey Pooling
32296183
种属内
TEX14 Q8IWB6 LHX3 Homo sapiens Q9UBR4-2
Y2H Array
32296183
种属内
TEX14 Q8IWB6 LHX3 Homo sapiens Q9UBR4-2
Validated Y2H
32296183
种属内
TEX14 Q8IWB6 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
种属内
TEX14 Q8IWB6 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
种属内
TEX14 Q8IWB6 LMO4 Homo sapiens P61968
Y2H Prey Pooling
32296183
种属内
TEX14 Q8IWB6 LMO4 Homo sapiens P61968
Y2H Array
32296183
种属内
TEX14 Q8IWB6 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
种属内
TEX14 Q8IWB6 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
种属内
TEX14 Q8IWB6 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
种属内
TEX14 Q8IWB6 CEP55 Homo sapiens Q53EZ4
Pull Down
32707033
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spermatogenic Failure 23

SPGF23
Male Infertility With Azoospermia Or Oligozoospermia Due To Single Gene Mutation
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Spermatogenic Failure 5

Male Infertility With Large-Headed, Multiflagellar, Polyploid Spermatozoa

Infertility Associated With Multi-Tailed Spermatozoa And Excessive Dna

SPGF5

Macrocephalic Sperm Head Syndrome

Male Infertility Due To Macrozoospermia

Infertility Associated With Multitailed Spermatozoa And Excessive Dna

Macrozoospermia

Male Infertility Due To Large-Headed Multiflagellar Polyploid Spermatozoa

Infertility Associated With Multi-Tailed Spermatozoa And Excessive Deoxyribonucleic Acid

Large-Headed Multiflagellar Polyploid Spermatozoa

Male Infertility With Large-Headed Multiflagellar Polyploid Spermatozoa
Spermatogenic Failure, X-Linked, 1

Sertoli Cell-Only Syndrome

Germinal Cell Aplasia

Del Castillo Syndrome

SPGFX1

X-Linked Spermatogenic Failure 1

Congenital Absence Of Germinal Epithelium Of Testes
Orchitis

Inflammation Of Testis

Orchititis

Mumps Orchitis
Hemochromatosis, Type 1

Hemochromatosis

Hemochromatosis Type 1

Hereditary Hemochromatosis

Hh

HFE1

Hfe Hemochromatosis, Modifier Of

Symptomatic Form Of Classic Hemochromatosis

Symptomatic Form Of Hemochromatosis Type 1

Symptomatic Form Of Hfe-Related Hereditary Hemochromatosis

Haemochromatosis

Iron Storage Disorder

Bronze Diabetes

Hereditary Haemochromatosis

Hlah

Hfe

Hemochromatosis, Hereditary

Diabetes Bronze

Classic Hemochromatosis

Hfe-Associated Hereditary Hemochromatosis

Hemochromatosis Classic

Bronzed Cirrhosis

Familial Hemochromatosis

Genetic Hemochromatosis

Hc

Pigmentary Cirrhosis

Primary Hemochromatosis

Troisier-Hanot-Chauffard Syndrome

Von Recklenhausen-Applebaum Disease

Hemochromatosis 1

Primary Hereditary Hemochromatosis

Bronze Cirrhosis
Vas Deferens, Congenital Bilateral Aplasia Of

Congenital Bilateral Absence Of Vas Deferens

CBAVD

Cavd

Congenital Bilateral Aplasia Of Vas Deferens

Congenital Bilateral Absence Of The Vas Deferens

Congenital Bilateral Agenesis Of Vas Deferens

Absence Of Vas Deferens

Absent Vasa

Congenital Absence Of Vas Deferens

Congenital Aplasia Of Vas Deferens

Absent Vas Deferens

Vas Deferens, Congenital Bilateral Absence
Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism

Undescended Testicle

Undescended Testis

Cryptorchism

Undescended Testicles

CRYPTO

Impaired Testicular Descent

Cryptosporidiosis

Retained Testis

Unilateral Cryptorchidism

Unilateral Undescended Testis

Nondescent Unilateral Testicle

Unilateral Cryptorchism

Ectopic Testis, Unilateral

Bilateral Cryptorchidism

Bilateral Cryptorchism

Bilateral Nondescent Testicle

Bilateral Undescended Testes

Bilateral Ectopic Testes
Galloway-Mowat Syndrome

Galloway Mowat Syndrome

Galloway Syndrome

Hiatal Hernia-Microcephaly-Nephrosis, Galloway Type

Microcephaly Nephrosis Syndrome

Microcephaly, Hiatal Hernia, And Nephrotic Syndrome

Nephrosis Neuronal Dysmigration Syndrome

Microcephaly-Hiatus Hernia-Nephrotic Syndrome

Nephrosis-Neuronal Dysmigration Syndrome
Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14391 TEX14 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus TEX14 VGNC VGNC:97659
Rattus norvegicus TEX14 RGD RGD:1305437
Mus musculus TEX14 MGD MGI:1933227
Bos taurus TEX14 VGNC VGNC:35762
Macaca mulatta TEX14 VGNC VGNC:99297
Canis familiaris TEX14 VGNC VGNC:47267
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