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  2. PRM1 - protamine 1 Gene

PRM1 - protamine 1 Gene

中文名称:鱼精蛋白 1

种属: Homo sapiens

同用名: P1; CT94.1

基因 ID: 5619 | 基因类型: protein coding

关于 PRM1

Cytogenetic location: 16p13.13 Genomic coordinates (GRCh38): 16:11,280,841-11,281,330 (from NCBI)

This gene has 1 transcript (splice variant) and 17 orthologues. Restricted expression toward testis (RPKM 2212.7).

功能概要

预测启用 DNA 结合活性。预计参与 DNA 包装。预计在细胞核组织和精子细胞发育的上游或内部起作用。位于细胞质和核质中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable DNA binding activity. Predicted to be involved in DNA packaging. Predicted to act upstream of or within nucleus organization and spermatid development. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PRM1 基因产物(1)

mRNA Protein Name
NM_002761.3 NP_002752.1 sperm protamine P1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PRM1 蛋白结构

Protamine_P1

Protamine_P1: Protamine P1 (2 - 50)

  • 0
  • 51 a.a.
蛋白主名 其他名称

sperm protamine P1

cancer/testis antigen family 94, member 1

PRM1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PRM1 P04553 CLK2 Homo sapiens P49760 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility

Infertility
Varicocele

Scrotal Varices

Varicoceles

Varicocele Of Scrotum

Scrotal Varicocele

Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism

Nickel Allergic Contact Dermatitis

Allergic Contact Dermatitis To Ni

Pelvic Varices

Varix Of Pelvis

Pelvic Varicose Vein

Oligoasthenoteratozoospermia

Oat

Oligoasthenoteratospermia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus PRM1 MGD MGI:97765
Rattus norvegicus PRM1 RGD RGD:1583873
Others PRM1 NCBI