2. Gene
  3. GKN1 - gastrokine 1 Gene

GKN1 - gastrokine 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：胃泌素 1

种属: Homo sapiens

同用名: FOV; CA11; AMP18; BRICD1; foveolin

基因 ID: 56287 | 基因类型: protein coding

关于 GKN1

Cytogenetic location: 2p13.3 Genomic coordinates (GRCh38): 2:68,974,636-68,980,976 (from NCBI)

This gene has 3 transcripts (splice variants), 126 orthologues and 2 paralogues. Restricted expression toward stomach (RPKM 11425.3).

功能概要

与正常胃粘膜相比，发现由该基因编码的蛋白质在人胃癌组织中下调。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is found to be down-regulated in human gastric Cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008]

GKN1 基因产物(1)

mRNA Protein Name
NM_019617.4 NP_062563.4 gastrokine-1 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
15221938 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GKN1 蛋白结构

BRICHOS

BRICHOS: BRICHOS domain (68 - 163)

  • 0
  • 100
  • 199 a.a.
蛋白主名 其他名称

gastrokine-1

18 kDa antrum mucosa protein

重组 GKN1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76356 Gastrokine 1 Protein, Human (sf9, His) Q9NS71 (N35-N199) ≥95%

关联疾病

疾病名称 别名
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
Granulomatous Disease, Chronic, Autosomal Recessive, 2

Chronic Granulomatous Disease Due To Deficiency Of Ncf-2

CGD2

Ncf2 Deficiency

P67-Phox Deficiency

Autosomal Recessive Chronic Granulomatous Disease Cytochrome B-Positive Type Ii

Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type 2

Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type Ii

Cgd, Autosomal Recessive Cytochrome B-Positive, Type Ii

Granulomatous Disease, Chronic, Due To Ncf2 Deficiency

Neutrophil Cytosol Factor 2 Deficiency

Chronic Granulomatous Disease 2, Autosomal Recessive

Autosomal Recessive Chronic Granulomatous Disease 2

Cdg2

Deficiency Of Ncf2

Deficiency Of P67-Phox

Chronic Granulomatous Disease Autosomal Recessive Cytochrome B-Positive Type Ii

Deficiency Of Neutrophil Cytosol Factor 2

Avellino Corneal Dystrophy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05461 GKN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris GKN1 VGNC VGNC:41246
Mus musculus GKN1 MGD MGI:1913533
Bos taurus GKN1 VGNC VGNC:29388
Felis catus GKN1 VGNC VGNC:62570
Rattus norvegicus GKN1 RGD RGD:735014
Others GKN1 NCBI
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