2. Gene
  3. SLC7A10 - solute carrier family 7 member 10 Gene

SLC7A10 - solute carrier family 7 member 10 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 7 成员 10

种属: Homo sapiens

同用名: ASC1; asc-1; HASC-1

基因 ID: 56301 | 基因类型: protein coding

关于 SLC7A10

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:33,208,664-33,225,850 (from NCBI)

This gene has 5 transcripts (splice variants), 301 orthologues and 12 paralogues. Broad expression in fat (RPKM 24.7), ovary (RPKM 10.1) and 14 other tissues.

功能概要

SLC7A10 与 4F2HC (SLC3A2；MIM 158070) 结合，介导 D-丝氨酸和其他几种中性氨基酸的高亲和力转运 (Nakauchi 等人，2000 [PubMed 10863037]) 。[OMIM 提供，2008 年 3 月]

SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral Amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]

SLC7A10 基因产物(1)

mRNA Protein Name
NM_019849.3 NP_062823.1 asc-type amino acid transporter 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables neutral L-amino acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
10863037 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in neutral amino acid transport IDA
IDA: 通过直接分析推断
10863037 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC7A10 蛋白结构

AA_permease_2

AA_permease_2: Amino acid permease (40 - 443)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 523 a.a.
蛋白主名 其他名称

asc-type amino acid transporter 1

solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10

关联疾病

疾病名称 别名
Cystinuria

CSNU

Cystinuria Type B

Cystinuria Type A

Cystinuria, Type I, Formerly

Csnu1, Formerly

Cystinuria, Type Ii, Formerly

Cystinuria, Type Iii, Formerly

Csnu3, Formerly

Cystinuria, Type Non-I, Formerly

Cystinuria-Lysinuria

Cystinuria-Lysinuria Syndrome

Csnu1

Csnu3

Cystinuria 1

Cystinuria Type A/B

Cystinuria Type I

Cystinuria Type Ii

Cystinuria Type Iii

Cystinuria Type Non-I

Cystinuria, Type A/B

Cystinuria Type 1

Cystinuria - Lysinuria

Csnu - [Cystinuria]

Cystine Disease
Hyperekplexia

Hereditary Hyperekplexia

Kok Disease

Congenital Stiff Man Syndrome

Familial Startle Disease

Sthe

Stiff-Baby Syndrome

Hereditary Hyperexplexia

Startle Disease

Exaggerated Startle Reaction

Hyperexplexia Hereditary

Startle Disease, Familial

Startle Reaction, Exaggerated

Stiff-Man Syndrome, Congenital

Stiff-Person Syndrome, Congenital

Congenital Stiff-Man Syndrome

Congenital Stiff-Person Syndrome

Familial Hyperekplexia

Startle Syndrome

Stiff Baby Syndrome

Hyperekplexia, Hereditary

Stiff-Person Syndrome
Hypotonia-Cystinuria Syndrome

Cystinuria With Mitochondrial Disease

2p21 Microdeletion Syndrome

HCS

Homozygous 2p16 Deletion Syndrome, Formerly

2p21 Deletion Syndrome

Del(2)(P21)

Monosomy 2p21

Atypical Hypotonia-Cystinuria Syndrome

Atypical Hcs
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120170 BMS-466442 Inhibitor 98.99% 否
HY-RS13324 SLC7A10 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SLC7A10 MGD MGI:1858261
Canis familiaris SLC7A10 VGNC VGNC:46471
Bos taurus SLC7A10 VGNC VGNC:34925
Felis catus SLC7A10 VGNC VGNC:65422
Rattus norvegicus SLC7A10 RGD RGD:621672
Macaca mulatta SLC7A10 VGNC VGNC:77627
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