PRPSAP1 - phosphoribosyl pyrophosphate synthetase associated protein 1 Gene

中文名称：磷酸核糖焦磷酸合成酶相关蛋白 1

种属: Homo sapiens

同用名: PAP39

基因 ID: 5635 | 基因类型: protein coding

关于 PRPSAP1

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:76,309,478-76,354,198 (from NCBI)

This gene has 12 transcripts (splice variants), 280 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 21.2), testis (RPKM 17.1) and 25 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与 5-磷酸核糖 1-二磷酸生物合成过程和嘌呤核苷酸生物合成过程。预测是核糖磷酸二磷酸激酶复合物的一部分。预计在细胞质中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and purine nucleotide biosynthetic process. Predicted to be part of ribose phosphate diphosphokinase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PRPSAP1 基因产物(3)

mRNA	Protein	Name
NM_001330503.2	NP_001317432.1	phosphoribosyl pyrophosphate synthase-associated protein 1 isoform 2
NM_001366236.2	NP_001353165.1	phosphoribosyl pyrophosphate synthase-associated protein 1 isoform 2
NM_002766.3	NP_002757.2	phosphoribosyl pyrophosphate synthase-associated protein 1 isoform 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables identical protein binding	IPI IPI: 通过物理相互作用推断	16189514	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	16189514	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PRPSAP1 蛋白结构

Pribosyltran_N

Pribosyl_synth

0
100
200
300
385 a.a.

蛋白主名

其他名称

phosphoribosyl pyrophosphate synthase-associated protein 1

39 kDa phosphoribosypyrophosphate synthase-associated protein

PRPSAP1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	PRPSAP1	Q14558	UBE2I	Homo sapiens	Q7KZS0	Y2H Prey Pooling	32296183
种属内	PRPSAP1	Q14558	UBE2I	Homo sapiens	Q7KZS0	Validated Y2H	32296183
种属内	PRPSAP1	Q14558	UBE2I	Homo sapiens	Q7KZS0	Y2H Array	32296183
种属内	PRPSAP1	Q14558	CAPN7	Homo sapiens	Q9Y6W3	Validated Y2H	32296183
种属内	PRPSAP1	Q14558	PRPS2	Homo sapiens	P11908	Anti Tag CoIP	33961781
种属内	PRPSAP1	Q14558	PRPSAP1	Homo sapiens	Q14558	Y2H Pooling	16189514
种属内	PRPSAP1	Q14558	PRPSAP1	Homo sapiens	Q14558	Y2H Pooling	19447967
种属内	PRPSAP1	Q14558	PRPS1	Homo sapiens	P60891	Y2H Array	31515488
种属内	PRPSAP1	Q14558	PRPSAP1	Homo sapiens	Q14558	Y2H Prey Pooling	32296183
种属内	PRPSAP1	Q14558	PRPSAP1	Homo sapiens	Q14558	Validated Y2H	32296183
种属内	PRPSAP1	Q14558	PRPSAP1	Homo sapiens	Q14558	Y2H Array	32296183
种属内	PRPSAP1	Q14558	PRPSAP2	Homo sapiens	O60256	Y2H Prey Pooling	32296183
种属内	PRPSAP1	Q14558	PRPSAP2	Homo sapiens	O60256	Y2H Array	32296183
种属内	PRPSAP1	Q14558	PRPSAP2	Homo sapiens	O60256	Anti Tag CoIP	33961781
种属内	PRPSAP1	Q14558	MAGOHB	Homo sapiens	Q96A72	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

Bardet-Biedl Syndrome 7

BBS7	Bardet-Biedl Syndrome, Type 7

Charcot-Marie-Tooth Disease, X-Linked Recessive, 5

CMTX5	Rosenberg-Chutorian Syndrome
Charcot-Marie-Tooth Disease X-Linked Recessive 5	Optic Atrophy, Polyneuropathy, And Deafness
Charcot-Marie-Tooth Neuropathy X-Linked Recessive 5	Cmt5x
X-Linked Charcot-Marie-Tooth Disease Type 5	Charcot-Marie-Tooth Neuropathy, X-Linked Recessive, 5
Optic Atrophy Polyneuropathy Deafness	Optic Atrophy With Polyneuropathy And Deafness
Charcot-Marie-Tooth Disease, X-Linked Recessive, Type 5

Arts Syndrome

ARTS	Mrxsarts
Ataxia, Fatal X-Linked, With Deafness And Loss Of Vision	Mrxs18
Lethal Ataxia With Deafness And Optic Atrophy	Fatal X-Linked Ataxia With Deafness And Loss Of Vision
Mental Retardation, X-Linked, Syndromic, Arts Type	Mental Retardation, X-Linked, Syndromic 18
Syndromic X-Linked Mental Retardation 18	Syndromic X-Linked Mental Retardation Arts Type
Lethal Ataxia-Deafness-Optic Atrophy	X-Linked Fatal Ataxia With Deafness And Loss Of Vision
Ataxia-Deafness-Optic Atrophy, Lethal	Lethal Ataxia With Hearing Loss And Optic Atrophy
Art

Deafness, X-Linked 1

DFNX1	Dfn2
Deafness, X-Linked 2, Sensorineural Congenital	X-Linked Deafness 1
X-Linked Sensorineural Congenital Deafness 2	Deafness, X-Linked, 1
Congenital Sensorineural Deafness X-Linked 2	Deafness, X-Linked, Type 1

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS11221	PRPSAP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	PRPSAP1	VGNC	VGNC:45034
Bos taurus	PRPSAP1	VGNC	VGNC:33386
Macaca mulatta	PRPSAP1	VGNC	VGNC:76429
Rattus norvegicus	PRPSAP1	RGD	RGD:620206
Mus musculus	PRPSAP1	MGD	MGI:1915013
Felis catus	PRPSAP1	VGNC	VGNC:97569

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

PRPSAP1 - phosphoribosyl pyrophosphate synthetase associated protein 1 Gene

关于 PRPSAP1

功能概要

PRPSAP1 基因产物(3)

PRPSAP1 蛋白结构

PRPSAP1 蛋白互作信息

关联疾病

直系同源

热门区域

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PRPSAP1 - phosphoribosyl pyrophosphate synthetase associated protein 1 Gene

关于 PRPSAP1

功能概要

PRPSAP1 基因产物(3)

PRPSAP1 蛋白结构

PRPSAP1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z