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  2. EIF5A2 - eukaryotic translation initiation factor 5A2 Gene

EIF5A2 - eukaryotic translation initiation factor 5A2 Gene

中文名称:真核翻译起始因子 5A2

种属: Homo sapiens

同用名: EIF-5A2; eIF5AII

基因 ID: 56648 | 基因类型: protein coding

关于 EIF5A2

Cytogenetic location: 3q26.2 Genomic coordinates (GRCh38): 3:170,888,418-170,908,637 (from NCBI)

This gene has 5 transcripts (splice variants), 171 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 2.4), testis (RPKM 2.3) and 25 other tissues.

功能概要

预测启用翻译延伸因子活动。预计参与平移延伸的正调控。位于细胞内膜界的细胞器中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable translation elongation factor activity. Predicted to be involved in positive regulation of translational elongation. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

EIF5A2 基因产物(1)

mRNA Protein Name
NM_020390.6 NP_065123.1 eukaryotic translation initiation factor 5A-2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14622290 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

EIF5A2 蛋白结构

eIF-5a

eIF-5a: Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold (83 - 150)

  • 0
  • 100
  • 153 a.a.
蛋白主名 其他名称

eukaryotic translation initiation factor 5A-2

eIF-5A-2

重组 EIF5A2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70910 EIF5A2 Protein, Human (His) Q9GZV4 (M1-K153) ≥95%

关联疾病

疾病名称 别名
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris EIF5A2 VGNC VGNC:40293
Rattus norvegicus EIF5A2 RGD RGD:1306196
Felis catus EIF5A2 VGNC VGNC:61798
Bos taurus EIF5A2 VGNC VGNC:28419
Macaca mulatta EIF5A2 VGNC VGNC:72198
Mus musculus EIF5A2 MGD MGI:1933735
Others EIF5A2 NCBI