2. Gene
  3. PSMG2 - proteasome assembly chaperone 2 Gene

PSMG2 - proteasome assembly chaperone 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白酶体装配伴侣 2

种属: Homo sapiens

同用名: PAC2; HCCA3; CLAST3; MDS003; PRAAS4; HsT1707; TNFSF5IP1

基因 ID: 56984 | 基因类型: protein coding

关于 PSMG2

Cytogenetic location: 18p11.21 Genomic coordinates (GRCh38): 18:12,658,738-12,725,740 (from NCBI)

This gene has 23 transcripts (splice variants), 218 orthologues and is associated with 1 phenotype. Ubiquitous expression in testis (RPKM 46.4), bone marrow (RPKM 28.3) and 25 other tissues.

功能概要

启用分子适配器活动。参与分子伴侣介导的蛋白质复合物组装。位于核内。伴侣复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables molecular adaptor activity. Involved in chaperone-mediated protein complex assembly. Located in nucleus. Part of chaperone complex. [provided by Alliance of Genome Resources, Apr 2022]

PSMG2 基因产物(2)

mRNA Protein Name
NM_020232.5 NP_064617.2 proteasome assembly chaperone 2 isoform 1
NM_147163.2 NP_671692.1 proteasome assembly chaperone 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables molecular adaptor activity IGI
IGI: 通过遗传相互作用推断
17189198 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16251969 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chaperone-mediated protein complex assembly IDA
IDA: 通过直接分析推断
16251969 GOA
involved in chaperone-mediated protein complex assembly IGI
IGI: 通过遗传相互作用推断
17189198 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of protein folding chaperone complex IDA
IDA: 通过直接分析推断
16251969 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PSMG2 蛋白结构

PAC2

PAC2: PAC2 family (17 - 226)

  • 0
  • 100
  • 200
  • 264 a.a.
蛋白主名 其他名称

proteasome assembly chaperone 2

CD40 ligand-activated specific transcript 3

PSMG2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PSMG2 Q969U7 TCF4 Homo sapiens P15884
Validated Y2H
25416956
种属内
PSMG2 Q969U7 TCF4 Homo sapiens P15884
Y2H Prey Pooling
25416956
种属内
PSMG2 Q969U7 PSMG1 Homo sapiens O95456
Anti Tag CoIP
33961781
种属内
PSMG2 Q969U7 PSMG1 Homo sapiens O95456
Y2H Prey Pooling
32296183
种属内
PSMG2 Q969U7 PSMG1 Homo sapiens O95456
Anti Tag CoIP
35271311
种属内
PSMG2 Q969U7 PSMG1 Homo sapiens O95456
Y2H Array
32296183
种属内
PSMG2 Q969U7 NOTCH2NLA Homo sapiens Q7Z3S9
Y2H Prey Pooling
25416956
种属内
PSMG2 Q969U7 NOTCH2NLA Homo sapiens Q7Z3S9
Validated Y2H
25416956
种属内
PSMG2 Q969U7 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
种属内
PSMG2 Q969U7 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
种属内
PSMG2 Q969U7 KRT31 Homo sapiens Q15323
Y2H Array
25416956
种属内
PSMG2 Q969U7 KRT31 Homo sapiens Q15323
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Proteasome-Associated Autoinflammatory Syndrome 4

PRAAS4
Panniculitis

Nodular Panniculitis
Proteasome-Associated Autoinflammatory Syndrome

Aldd Syndrome

Autoinflammation-Lipodystrophy-Dermatosis Syndrome

Praas

Proteasome Disability Syndrome
Solitary Median Maxillary Central Incisor

SMMCI

Fused Incisors

Single Upper Central Incisor

Single Central Maxillary Incisor

Single Median Maxillary Central Incisor

Solitary Median Maxillary Central Incisor Syndrome

Incisors Fused

Incisors, Fused
Hemolytic Anemia

Anemia, Hemolytic

Anemia Hemolytic

Anaemia Due To Other Disorders Of Glutathione Metabolism

Chronic Non Spherocytic Anaemia

G6pd - [Glucose-6-Phosphate Dehydrogenase Deficiency] Anaemia

Anaemia Due To Glucose-6-Phosphate Dehydrogenase Deficiency

Glucose-6-Phosphate Dehydrogenase Deficiency With Anaemia

Glucose-6-Phosphate Dehydrogenase Deficiency Anaemia

Favism Anaemia

Haemolytic Anaemia Due Tog6pd Deficiency

Favism

Pentose Phosphate Pathway Disorder Anaemia

Anaemia Due To Pentose Phosphate Pathway Defect
Basal Ganglia Calcification

Fahr'S Syndrome

Fahr'S Disease

Fahr Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11337 PSMG2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus PSMG2 VGNC VGNC:33479
Rattus norvegicus PSMG2 RGD RGD:1304867
Mus musculus PSMG2 MGD MGI:1922901
Felis catus PSMG2 VGNC VGNC:107719
Canis familiaris PSMG2 VGNC VGNC:45122
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