2. Gene
  3. PSMG1 - proteasome assembly chaperone 1 Gene

PSMG1 - proteasome assembly chaperone 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白酶体装配伴侣 1

种属: Homo sapiens

同用名: PAC1; DSCR2; PAC-1; C21LRP; LRPC21

基因 ID: 8624 | 基因类型: protein coding

关于 PSMG1

Cytogenetic location: 21q22.2 Genomic coordinates (GRCh38): 21:39,174,769-39,183,514 (from NCBI)

This gene has 5 transcripts (splice variants) and 193 orthologues. Broad expression in testis (RPKM 57.7), thyroid (RPKM 14.4) and 23 other tissues.

功能概要

启用分子适配器活动。参与分子伴侣介导的蛋白质复合物组装。位于多种细胞成分中，包括高尔基体；内质网；和核质。伴侣复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables molecular adaptor activity. Involved in chaperone-mediated protein complex assembly. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and nucleoplasm. Part of chaperone complex. [provided by Alliance of Genome Resources, Apr 2022]

PSMG1 基因产物(4)

mRNA Protein Name
NM_001261824.1 NP_001248753.1 proteasome assembly chaperone 1 isoform 3
NM_001320795.1 NP_001307724.1 proteasome assembly chaperone 1 isoform d
NM_003720.4 NP_003711.1 proteasome assembly chaperone 1 isoform a
NM_203433.2 NP_982257.1 proteasome assembly chaperone 1 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables molecular adaptor activity IDA
IDA: 通过直接分析推断
16251969 GOA
enables molecular adaptor activity IGI
IGI: 通过遗传相互作用推断
17189198 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16251969 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chaperone-mediated protein complex assembly IDA
IDA: 通过直接分析推断
16251969 GOA
involved in chaperone-mediated protein complex assembly IGI
IGI: 通过遗传相互作用推断
17189198 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15670775 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
15590417 GOA
part of protein folding chaperone complex IDA
IDA: 通过直接分析推断
16251969 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

proteasome assembly chaperone 1

Down syndrome critical region gene 2

PSMG1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PSMG1 O95456 PRKAR1B Homo sapiens P31321
Validated Y2H
32296183
种属内
PSMG1 O95456 PRKAR1B Homo sapiens P31321
Y2H Prey Pooling
32296183
种属内
PSMG1 O95456 PRKAR1B Homo sapiens P31321
Y2H Array
32296183
种属内
PSMG1 O95456 PSMG2 Homo sapiens Q969U7
Y2H Fragment Pooling
35914814
种属内
PSMG1 O95456 PSMG2 Homo sapiens Q969U7
Y2H Prey Pooling
32296183
种属内
PSMG1 O95456 PSMG2 Homo sapiens Q969U7
Validated Y2H
32296183
种属内
PSMG1 O95456 PSMG2 Homo sapiens Q969U7
Anti Tag CoIP
35271311
种属内
PSMG1 O95456 PSMG2 Homo sapiens Q969U7
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Down Syndrome

Trisomy 21

Complete Trisomy 21 Syndrome

Down'S Syndrome

Trisomy 21 Syndrome

Down'S Syndrome - Trisomy 21

Downs Syndrome

G Trisomy

47,Xx,+21

47,Xy,+21

Trisomy G

Down Syndrome, Susceptibility To

Chromosome 21 Trisomy

Trisomy 21 Nos

Abnormal Autosomes 21
Thrombasthenia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11336 PSMG1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PSMG1 RGD RGD:1305454
Bos taurus PSMG1 VGNC VGNC:33478
Mus musculus PSMG1 MGD MGI:1860263
Macaca mulatta PSMG1 VGNC VGNC:76347
Canis familiaris PSMG1 VGNC VGNC:45121
Felis catus PSMG1 VGNC VGNC:102810
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