1. Gene
  2. TOMM22 - translocase of outer mitochondrial membrane 22 Gene

TOMM22 - translocase of outer mitochondrial membrane 22 Gene

中文名称:线粒体外膜转位酶 22

种属: Homo sapiens

同用名: 1C9-2; TOM22; MST065; MSTP065

基因 ID: 56993 | 基因类型: protein coding

关于 TOMM22

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:38,681,957-38,685,421 (from NCBI)

This gene has 2 transcripts (splice variants) and 213 orthologues. Ubiquitous expression in colon (RPKM 24.2), kidney (RPKM 23.3) and 25 other tissues.

功能概要

该基因编码的蛋白质是线粒体外膜的完整膜蛋白。编码的蛋白质与 TOMM20 和 TOMM40 相互作用,并与其他几种蛋白质形成复合物,将细胞溶质前蛋白导入线粒体。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq, Jul 2008]

TOMM22 基因产物(1)

mRNA Protein Name
NM_020243.5 NP_064628.1 mitochondrial import receptor subunit TOM22 homolog

TOMM22 蛋白结构

Tom22

Tom22: Mitochondrial import receptor subunit Tom22 (24 - 117)

  • 0
  • 100
  • 142 a.a.
蛋白主名 其他名称

mitochondrial import receptor subunit TOM22 homolog

mitochondrial import receptor Tom22

TOMM22 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TOMM22 Q9NS69 TOMM7 Homo sapiens Q9P0U1
BN-PAGE
12198123
Intra TOMM22 Q9NS69 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra TOMM22 Q9NS69 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
3-Methylglutaconic Aciduria, Type V

3-Methylglutaconic Aciduria Type 5

Mga5

MGCA5

Dcma

Dcma Syndrome

Dilated Cardiomyopathy With Ataxia

3-Methylglutaconic Aciduria Type V

Mga Type V

Cardiomyopathy, Dilated, With Ataxia

Mga, Type V

Dilated Cardiomyopathy With Ataxia Syndrome

Dnajc19 Defect

3-Methylglutaconic Aciduria 5

3-Alpha-Methylglutaconic Aciduria Type 5

3-@Methylglutaconic Aciduria, Type V

3-Methylglutaconic Aciduria, Type Iii

Optic Atrophy

3-Methylglutaconic Aciduria Type 3

Costeff Syndrome

Mga3

Costeff Optic Atrophy Syndrome

Optic Atrophy Plus Syndrome

Infantile Optic Atrophy With Chorea And Spastic Paraplegia

3-Methylglutaconic Aciduria Type Iii

Autosomal Recessive Optic Atrophy Plus Syndrome

Autosomal Recessive Optic Atrophy Type 3

Opa3 Defect

MGCA3

Mga, Type Iii

Iraqi Jewish Optic Atrophy Plus

Mga Type Iii

Optic Atrophy, Infantile, With Chorea And Spastic Paraplegia

Iraqi-Jewish 'Optic Atrophy Plus'

Optic Atrophy 3, Autosomal Recessive

Opa3, Autosomal Recessive

Opa3-Related 3-Methylglutaconic Aciduria

Iraqi-Jewish Optic Atrophy Plus

Atrophy Of Optic Disc

3-Alpha Methylglutaconic Aciduria Type Iii

Optic Atrophy 3

Optic Atrophy Infantile With Chorea And Spastic Paraplegia

Autosomal Recessive Opa3

Autosomal Recessive Optic Atrophy 3

3-Methylglutaconic Aciduria 3

3-Alpha-Methylglutaconic Aciduria Type 3

Optic Atrophy 3 Autosomal Recessive

Atrophy, Optic

Atrophy, Optic, Plus Syndrome

Optic Nerve Atrophy

Primary Optic Atrophy

Oa - [Optic Atrophy]

Second Cranial Nerve Atrophy

Second Cranium Nerve Atrophy

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus TOMM22 VGNC VGNC:49064
Felis catus TOMM22 VGNC VGNC:66443
Macaca mulatta TOMM22 VGNC VGNC:98461
Mus musculus TOMM22 MGD MGI:2450248
Rattus norvegicus TOMM22 RGD RGD:1303260