1. Gene
  2. TOMM7 - translocase of outer mitochondrial membrane 7 Gene

TOMM7 - translocase of outer mitochondrial membrane 7 Gene

中文名称:线粒体外膜转位酶 7

种属: Homo sapiens

同用名: TOM7

基因 ID: 54543 | 基因类型: protein coding

关于 TOMM7

Cytogenetic location: 7p15.3 Genomic coordinates (GRCh38): 7:22,812,974-22,822,849 (from NCBI)

This gene has 6 transcripts (splice variants) and 187 orthologues. Ubiquitous expression in ovary (RPKM 141.3), fat (RPKM 120.2) and 25 other tissues.

功能概要

该基因编码线粒体外膜转位酶的一个亚基。编码的蛋白质调节转位酶复合物的组装和稳定性。[RefSeq 提供,2012 年 10 月]

This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]

TOMM7 基因产物(1)

mRNA Protein Name
NM_019059.5 NP_061932.1 mitochondrial import receptor subunit TOM7 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12198123 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of protein targeting to mitochondrion IMP
IMP: 通过突变表型推断
24270810 GOA
involved in positive regulation of type 2 mitophagy IMP
IMP: 通过突变表型推断
24270810 GOA
involved in regulation of protein stability IMP
IMP: 通过突变表型推断
24270810 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of mitochondrial outer membrane translocase complex IDA
IDA: 通过直接分析推断
12198123 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
12198123 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TOMM7 蛋白结构

Tom7

Tom7: TOM7 family (9 - 53)

  • 0
  • 55 a.a.
蛋白主名 其他名称

mitochondrial import receptor subunit TOM7 homolog

translocase of outer membrane 7 kDa subunit homolog

TOMM7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TOMM7 Q9P0U1 TOMM22 Homo sapiens Q9NS69 12198123
种属内
TOMM7 Q9P0U1 TOMM20 Homo sapiens Q15388 30021884
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
3-Methylglutaconic Aciduria, Type Iii

Optic Atrophy

3-Methylglutaconic Aciduria Type 3

Costeff Syndrome

Mga3

Costeff Optic Atrophy Syndrome

Optic Atrophy Plus Syndrome

Infantile Optic Atrophy With Chorea And Spastic Paraplegia

3-Methylglutaconic Aciduria Type Iii

Autosomal Recessive Optic Atrophy Plus Syndrome

Autosomal Recessive Optic Atrophy Type 3

Opa3 Defect

MGCA3

Mga, Type Iii

Iraqi Jewish Optic Atrophy Plus

Mga Type Iii

Optic Atrophy, Infantile, With Chorea And Spastic Paraplegia

Iraqi-Jewish 'Optic Atrophy Plus'

Optic Atrophy 3, Autosomal Recessive

Opa3, Autosomal Recessive

Opa3-Related 3-Methylglutaconic Aciduria

Iraqi-Jewish Optic Atrophy Plus

Atrophy Of Optic Disc

3-Alpha Methylglutaconic Aciduria Type Iii

Optic Atrophy 3

Optic Atrophy Infantile With Chorea And Spastic Paraplegia

Autosomal Recessive Opa3

Autosomal Recessive Optic Atrophy 3

3-Methylglutaconic Aciduria 3

3-Alpha-Methylglutaconic Aciduria Type 3

Optic Atrophy 3 Autosomal Recessive

Atrophy, Optic

Atrophy, Optic, Plus Syndrome

Optic Nerve Atrophy

Primary Optic Atrophy

Oa - [Optic Atrophy]

Second Cranial Nerve Atrophy

Second Cranium Nerve Atrophy

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus TOMM7 MGD MGI:1913419
Felis catus TOMM7 VGNC VGNC:102724
Canis familiaris TOMM7 VGNC VGNC:54798
Macaca mulatta TOMM7 VGNC VGNC:108450
Rattus norvegicus TOMM7 RGD RGD:1591393