2. Gene
  3. TRPC7 - transient receptor potential cation channel subfamily C member 7 Gene

TRPC7 - transient receptor potential cation channel subfamily C member 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：瞬时受体电位阳离子通道亚家族 C 成员 7

种属: Homo sapiens

同用名: TRP7

基因 ID: 57113 | 基因类型: protein coding

关于 TRPC7

This gene has 7 transcripts (splice variants), 226 orthologues and 5 paralogues. Low expression observed in reference dataset.

功能概要

预计可启用肌醇 1,4,5 三磷酸结合活性和钙离子钙通道活性。预计参与金属离子传输；细胞溶质钙离子浓度的调节；和单一施肥。预计在钙离子传输的上游或内部起作用。预测位于质膜中。预计是阳离子通道复合体的一部分。预计是质膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated Calcium Channel activity. Predicted to be involved in metal ion transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within calcium ion transport. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TRPC7 基因产物(4)

mRNA Protein Name
NM_001167576.2 NP_001161048.1 short transient receptor potential channel 7 isoform 3
NM_001167577.2 NP_001161049.1 short transient receptor potential channel 7 isoform 2
NM_001376901.1 NP_001363830.1 short transient receptor potential channel 7 isoform 4
NM_020389.3 NP_065122.1 short transient receptor potential channel 7 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21402151 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRPC7 蛋白结构

Ank_2

Ank_2: Ankyrin repeats (3 copies) (51 - 128)

TRP_2

TRP_2: Transient receptor ion channel II (198 - 260)

Ion_trans

Ion_trans: Ion transport protein (442 - 672)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 862 a.a.
蛋白主名 其他名称

short transient receptor potential channel 7

likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111925 BI-749327 Antagonist 99.91% 否
HY-111527 PPZ2 99.70% 否
HY-162090 TRPC antagonist 1 Antagonist / 否
HY-RS15110 TRPC7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TRPC7 RGD RGD:628820
Bos taurus TRPC7 VGNC VGNC:36387
Canis familiaris TRPC7 VGNC VGNC:47872
Mus musculus TRPC7 MGD MGI:1349470
Felis catus TRPC7 VGNC VGNC:66587
Macaca mulatta TRPC7 VGNC VGNC:79280
Others TRPC7 NCBI
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