CAMK1D - calcium/calmodulin dependent protein kinase ID Gene

中文名称：钙/钙调蛋白依赖性蛋白激酶 ID

种属: Homo sapiens

同用名: CKLiK; CaM-K1; CaMKID

基因 ID: 57118 | 基因类型: protein coding

关于 CAMK1D

Cytogenetic location: 10p13 Genomic coordinates (GRCh38): 10:12,349,547-12,835,545 (from NCBI)

This gene has 3 transcripts (splice variants), 267 orthologues and 22 paralogues. Broad expression in brain (RPKM 10.9), skin (RPKM 4.6) and 21 other tissues.

功能概要

该基因是钙/钙调蛋白依赖性蛋白激酶 1 家族的成员，该家族是丝氨酸/苏氨酸激酶的一个亚家族。编码的蛋白质是钙调节的钙调蛋白依赖性蛋白激酶级联的组成部分。它与多种过程相关，包括粒细胞功能的调节、CREB 依赖性基因转录的激活、醛固酮的合成、中性粒细胞的分化和激活以及红白血病细胞的凋亡。已经描述了编码该基因的不同同种型的可变剪接转录物变体。[RefSeq 提供，2015 年 1 月]

This gene is a member of the calcium/calmodulin-dependent protein kinase 1 family, a subfamily of the serine/threonine kinases. The encoded protein is a component of the calcium-regulated calmodulin-dependent protein kinase cascade. It has been associated with multiple processes including regulation of granulocyte function, activation of CREB-dependent gene transcription, aldosterone synthesis, differentiation and activation of neutrophil cells, and Apoptosis of erythroleukemia cells. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jan 2015]

CAMK1D 基因产物(3)

mRNA	Protein	Name
NM_001351032.2	NP_001337961.1	calcium/calmodulin-dependent protein kinase type 1D isoform 3
NM_020397.4	NP_065130.1	calcium/calmodulin-dependent protein kinase type 1D isoform 1
NM_153498.4	NP_705718.1	calcium/calmodulin-dependent protein kinase type 1D isoform 2

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables calcium/calmodulin-dependent protein kinase activity	IDA IDA: 通过直接分析推断	11050006	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	32707033	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of CREB transcription factor activity	IDA IDA: 通过直接分析推断	16324104	GOA
involved in positive regulation of phagocytosis	IMP IMP: 通过突变表型推断	15840691	GOA
involved in positive regulation of respiratory burst	IMP IMP: 通过突变表型推断	15840691	GOA
involved in regulation of dendrite development	IMP IMP: 通过突变表型推断	17056143	GOA
involved in regulation of granulocyte chemotaxis	IMP IMP: 通过突变表型推断	15840691	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	11050006	GOA
located in nucleus	IDA IDA: 通过直接分析推断	16324104	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CAMK1D 蛋白结构

Pkinase

0
100
200
300
385 a.a.

蛋白主名

其他名称

calcium/calmodulin-dependent protein kinase type 1D

CAMK1D/ANAPC5 fusion

CAMK1D 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	CAMK1D	Q8IU85	CAMK1	Homo sapiens	Q14012	Pull Down	32707033
种属内	CAMK1D	Q8IU85	CAMK1	Homo sapiens	Q14012	Anti Tag CoIP	33961781

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CAMK1D 蛋白

目录号	产品名	蛋白编号	纯度
HY-P7715	CAMKI delta/CAMK1D Protein, Human (GST)	Q8IU85-1 (M1-K385)	≥95%

关联疾病

疾病名称

别名

Ceroid Lipofuscinosis, Neuronal, 6a

Neuronal Ceroid Lipofuscinosis 6	CLN6
Vlincl	Cln6 Disease
Ceroid Lipofuscinosis, Neuronal, 6	Late-Infantile Neuronal Ceroid Lipofuscinosis
CLN6A	Neuronal Ceroid Lipofuscinosis, Late Infantile, Variant
Neuronal Ceroid Lipofuscinosis 6a	Neuronal Ceroid Lipofuscinosis 6 Variable Age Of Onset
Cln6 Disease, Adult Kufs Type A	Cln6 Disease, Late Infantile
Neuronal Ceroid Lipofuscinosis, Gypsy/Indian Early Juvenile Variant	Ceroid Lipofuscinosis Neuronal 6
Cln6-Related Neuronal Ceroid Lipofuscinosis	Late Infantile Neuronal Ceroid Lipofuscinosis
Jansky-Bielschowsky Disease	Lincl
Late Infantile Ncl	Neuronal Ceroid Lipofuscinosis 6 With Variable Age At Onset
Variant Late-Onset Infantile Neuronal Ceroid Lipofuscinosis	Ceroid Lipofuscinosis, Neuronal, Late Infantile, Variant
Lipofuscinosis, Ceroid, Neuronal, Type 6	Ceroid Lipofuscinosis, Neuronal, 5

Wolfram Syndrome 1

WFS1	Didmoad
Wfs	Diabetes Mellitus And Insipidus With Optic Atrophy And Deafness
Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness	Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness Syndrome
Wolfram Syndrome

Type 2 Diabetes Mellitus

Insulin Resistance	NIDDM
Type 2 Diabetes	Diabetes Mellitus, Non-Insulin-Dependent
T2D	Noninsulin-Dependent Diabetes Mellitus
Diabetes Mellitus, Type Ii	Maturity-Onset Diabetes
Insulin Resistance, Severe, Digenic	Diabetes Mellitus, Type 2
Diabetes Mellitus, Noninsulin-Dependent	Diabetes Mellitus, Noninsulin-Dependent, Association With
Diabetes Mellitus, Noninsulin-Dependent, Late Onset	Hypertension, Insulin Resistance-Related, Susceptibility To
Insulin Resistance, Susceptibility To	Non-Insulin-Dependent Diabetes Mellitus
Type Ii Diabetes Mellitus	Adult-Onset Diabetes Mellitus
Maturity-Onset Diabetes Mellitus	Diabetes Mellitus Type 2
Type Ii Diabetes	Type 2 Diabetes Mellitus, Susceptibility To
Diabetes, Type 2	Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To
Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To	Diabetes Mellitus, Type 2, Susceptibility To
Diabetes Mellitus, Noninsulin-Dependent, 2	Diabetes Mellitus, Type Ii, Susceptibility To
Hypertension, Insulin Resistance-Related	Adult-Onset Diabetes
Aodm	Diabetes Mellitus, Adult-Onset
Diabetes Mellitus Type Ii	Diabetes Mellitus Type 2, Susceptibility To
Diabetes, Type Ii, Susceptibility To	Diabetes Type 2
Diabetes Mellitus	Adult Onset Diabetes
Maturity Onset Diabetes	Nonketotic Diabetes
Non-Insulin Dependent Diabetes Mellitus	T2dm - [Type 2 Diabetes Mellitus]
Niddm - [Non Insulin Dependent Diabetes Mellitus]	Dm2
Dm Type Ii	Diabetic Type 2
Insulin Requiring Type 2 Diabetes	Noninsulin Dependent Diabetes
Non-Insulin-Dependent Diabetes Mellitus Without Complications	Diabetes Due To Insulin Secretory Defect
Diabetes Mellitus Due To Insulin Secretory Defect	Non-Insulin-Dependent Diabetes Of The Young
Senile Diabetes	Nonketotic Hyperglycaemia
Stable Diabetes

Diabetes Mellitus

Diabetes

Maturity-Onset Diabetes Of The Young

MODY	Maturity Onset Diabetes Mellitus In Young
Mason-Type Diabetes	Mason Type Diabetes
Maturity Onset Diabetes Of The Young	Mody Syndrome
Diabetes Of The Young, Maturity-Onset

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-148913	CS587	Inhibitor	98.11%	否
HY-148907	CS640		99.43%	否
HY-156871	CAMK1D-IN-1		/	否
HY-RS01852	CAMK1D Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	CAMK1D	MGD	MGI:2442190
Bos taurus	CAMK1D	VGNC	VGNC:58595
Macaca mulatta	CAMK1D	VGNC	VGNC:70579
Rattus norvegicus	CAMK1D	RGD	RGD:1560691
Canis familiaris	CAMK1D	VGNC	VGNC:38678
Felis catus	CAMK1D	VGNC	VGNC:60329
Others	CAMK1D	NCBI

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CAMK1D - calcium/calmodulin dependent protein kinase ID Gene

关于 CAMK1D

功能概要

CAMK1D 基因产物(3)

CAMK1D 蛋白结构

CAMK1D 蛋白互作信息

重组 CAMK1D 蛋白

关联疾病

直系同源

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CAMK1D - calcium/calmodulin dependent protein kinase ID Gene

关于 CAMK1D

功能概要

CAMK1D 基因产物(3)

CAMK1D 蛋白结构

CAMK1D 蛋白互作信息

重组 CAMK1D 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z