2. Neuronal Signaling
  3. CaMK
  4. CAMK1D-IN-1

CAMK1D-IN-1 (compound I) 是 CAMK1D 的抑制剂，是靶向细胞毒性 T 淋巴细胞 (CTL) 产生抗性的肿瘤细胞。而 CAMK1D 则通过抑制 caspase 来削弱 CTL 诱导的死亡受体信号传导和细胞凋亡，是 PD-L1 难治性肿瘤的关键、有效靶点。

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CAMK1D-IN-1 Chemical Structure

CAMK1D-IN-1 Chemical Structure

CAS No. : 404828-08-6

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CAMK1D-IN-1 相关抗体

Top Publications Citing Use of Products

查看 CaMK 亚型特异性产品:

查看所有亚型
CaMK III CaMK II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CAMK1D-IN-1 (compound I) is an inhibitor of CAMK1D, targeting cytotoxic T lymphocyte (CTL)-resistant tumor cells. CAMK1D impairs CTL-induced death receptor signaling and apoptosis by inhibiting caspases, making it a key and effective target for PD-L1-refractory tumors[1].

分子量

305.38

Formula

C18H19N5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CAMK1D-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAMK1D-IN-1404828-08-6CaMKCalmodulin-dependent protein kinasesCalmodulin-dependent kinasesInhibitorsimmune checkpointApoptosisDeath receptor signalingCTL resistanceInhibitorinhibitorinhibit

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目录号：
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