HIVEP3 - HIVEP zinc finger 3 Gene

中文名称：HIVEP 锌指 3

种属: Homo sapiens

同用名: KRC; KBP1; SHN3; ZAS3; KBP-1; ZNF40C; Schnurri-3

关于 HIVEP3

功能概要

该基因编码人类免疫缺陷病毒 1 型增强子结合蛋白家族的成员。该蛋白质家族的成员包含多个锌指和富含酸 (ZAS) 结构域以及富含丝氨酸-苏氨酸的区域。这种蛋白质充当转录因子，能够通过结合目标基因中的 kappaB 基序来调节核因子 kappaB 介导的转录。该蛋白还结合位于免疫球蛋白和 T 细胞受体 V、D 和 J 区两侧的重组信号序列。交替剪接导致编码和非编码转录物变体。[RefSeq 提供，2011 年 9 月]

This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]