NTN4 - netrin 4 Gene

中文名称：netrin 4

种属: Homo sapiens

同用名: PRO3091

关于 NTN4

功能概要

该基因编码 netrin 蛋白家族的一个成员，该蛋白在各种生物过程中发挥作用，包括轴突导向、肿瘤发生和血管生成。 Netrins 是层粘连蛋白相关蛋白，具有 N 端层粘连蛋白型结构域、表皮生长因子样重复结构域和 C 端带正电荷的肝素结合结构域。由该基因编码的蛋白质参与包括神经突生长和迁移、血管生成和壁细胞与内皮细胞的粘附在内的过程。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 7 月]

This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]