2. Gene
  3. Cnksr2 - connector enhancer of kinase suppressor of Ras 2 Gene

Cnksr2 - connector enhancer of kinase suppressor of Ras 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 59322 | 基因类型: protein coding

关于 Cnksr2

功能概要

Enables identical protein binding activity. Involved in postsynapse organization. Located in several cellular components, including neuronal cell body; postsynaptic density; and postsynaptic membrane. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in syndromic X-linked mental retardation Hough type. Orthologous to human CNKSR2 (connector enhancer of kinase suppressor of Ras 2). [provided by Alliance of Genome Resources, Apr 2022]

Cnksr2 基因产物(2)

mRNA Protein Name
NM_001113366.1 NP_001106837.1 connector enhancer of kinase suppressor of ras 2 isoform 1
NM_021686.3 NP_067718.1 connector enhancer of kinase suppressor of ras 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12390249 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12390249 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in postsynapse organization IDA
IDA: 通过直接分析推断
24656827 RGD
involved in postsynapse organization IMP
IMP: 通过突变表型推断
24656827 RGD
involved in postsynaptic specialization organization IDA
IDA: 通过直接分析推断
32235845 RGD
involved in postsynaptic specialization organization IMP
IMP: 通过突变表型推断
32235845 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in extrinsic component of postsynaptic density membrane IDA
IDA: 通过直接分析推断
10207009 RGD
is active in extrinsic component of postsynaptic density membrane IMP
IMP: 通过突变表型推断
10207009 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
10207009 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
10207009 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
10207009 RGD
located in postsynaptic membrane IDA
IDA: 通过直接分析推断
10207009 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

connector enhancer of kinase suppressor of ras 2

CNK homolog protein 2

CNK2

connector enhancer of KSR 2

maguin

maguin-1

maguin-2

membrane-associated guanylate kinase-interacting protein

Cnksr2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Cnksr2 Q9Z1T4 Dlg4 Rattus norvegicus P31016
Anti Bait CoIP
12390249
Intra Cnksr2 Q9Z1T4 LRRC7 Homo sapiens Q96NW7
Pull Down
12390249
Intra Cnksr2 Q9Z1T4 Lrrc7 Rattus norvegicus P70587
Anti Bait CoIP
12390249
Intra Cnksr2 Q9Z1T4 Cnksr2 Rattus norvegicus Q9Z1T4
Y2H
12390249
Intra Cnksr2 Q9Z1T4 Cnksr2 Rattus norvegicus Q9Z1T4
Anti Tag CoIP
12390249
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02889 CNKSR2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cnksr2 NCBI NCBI:22866
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