1. Gene
  2. Lrrc7 - leucine rich repeat containing 7 Gene

Lrrc7 - leucine rich repeat containing 7 Gene

种属: Rattus norvegicus

基因 ID: 117284 | 基因类型: protein coding

关于 Lrrc7

功能概要

Enables protein C-terminus binding activity. Involved in positive regulation of neuron projection development and response to organic cyclic compound. Located in several cellular components, including axon initial segment; dendritic spine; and postsynaptic density. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Colocalizes with actin Cytoskeleton. Orthologous to human LRRC7 (leucine rich repeat containing 7). [provided by Alliance of Genome Resources, Apr 2022]

Lrrc7 基因产物(2)

mRNA Protein Name
NM_001393674.1 NP_001380603.1 leucine-rich repeat-containing protein 7 isoform 1
NM_057142.2 NP_476483.1 leucine-rich repeat-containing protein 7 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12390249 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
16120608 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
15647492 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
19038319 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
18248607 RGD
located in axon initial segment IDA
IDA: 通过直接分析推断
8824323 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
8824323 RGD
located in filopodium IDA
IDA: 通过直接分析推断
18248607 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
8824323 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
8824323 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leucine-rich repeat-containing protein 7

densin 13T-16

densin 13T-17

densin 13T-23

densin 13T-29

densin 13T-41

densin 13T-43

densin 13T-57

densin 13T-57C

densin 13T-72

densin 13T-89

densin-180

Lrrc7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Lrrc7 P70587 Camk2a Rattus norvegicus P11275
Anti Bait CoIP
16120608
Intra Lrrc7 P70587 Dlg4 Rattus norvegicus P31016
Anti Tag CoIP
12390249
Intra Lrrc7 P70587 Dlg4 Rattus norvegicus P31016
IF
12390249
Intra Lrrc7 P70587 Dlg4 Rattus norvegicus P31016
Anti Bait CoIP
12390249
Cross Lrrc7 P70587 Camk2a Mus musculus P11798
Filter Binding
16120608
Cross Lrrc7 P70587 Camk2a Mus musculus P11798
Pull Down
16120608
Intra Lrrc7 P70587 Cnksr2 Rattus norvegicus Q9Z1T4
Anti Bait CoIP
12390249
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrrc7 NCBI NCBI:57554