RBMS1 - RNA binding motif single stranded interacting protein 1 Gene

中文名称：RNA 结合基序单链相互作用蛋白 1

种属: Homo sapiens

同用名: YC1; MSSP; SCR2; HCC-4; MSSP-1; MSSP-2; MSSP-3; C2orf12

基因 ID: 5937 | 基因类型: protein coding

关于 RBMS1

Cytogenetic location: 2q24.2 Genomic coordinates (GRCh38): 2:160,272,151-160,493,807 (from NCBI)

This gene has 14 transcripts (splice variants), 270 orthologues and 24 paralogues. Ubiquitous expression in placenta (RPKM 34.9), endometrium (RPKM 27.3) and 24 other tissues.

功能概要

该基因编码一个小的蛋白质家族的成员，该家族的蛋白质结合单链 DNA/RNA。这些蛋白质的特点是存在两组核糖核蛋白共有序列 (RNP-CS) ，其中包含保守基序 RNP1 和 RNP2，最初在 RNA 结合蛋白中描述，并且是 DNA 结合所必需的。这些蛋白质涉及多种功能，如 DNA 复制、基因转录、细胞周期进程和细胞凋亡。已经描述了由可变剪接和编码不同同种型产生的几种转录物变体。在 12 号染色体上发现了该基因座的假基因。[RefSeq 提供，2009 年 2 月]

This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and Apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]

RBMS1 基因产物(2)

mRNA	Protein	Name
NM_002897.5	NP_002888.1	RNA-binding motif, single-stranded-interacting protein 1 isoform c
NM_016836.4	NP_058520.1	RNA-binding motif, single-stranded-interacting protein 1 isoform a

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	10869558	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RBMS1 蛋白结构

RRM_1

0
100
200
300
406 a.a.

蛋白主名

其他名称

RNA-binding motif, single-stranded-interacting protein 1

c-myc gene single strand binding protein 2

RBMS1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RBMS1	P29558	TFCP2	Homo sapiens	Q12800	Validated Y2H	25416956
种属内	RBMS1	P29558	TFCP2	Homo sapiens	Q12800	Y2H Array	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Diffuse Glomerulonephritis

Glomerulonephritis Diffuse

Microcephaly 2, Primary, Autosomal Recessive, With Or Without Cortical Malformations

MCPH2	Primary Autosomal Recessive Microcephaly 2 With Or Without Cortical Malformations
Microcephaly, Primary Autosomal Recessive, 2

Epidermolysis Bullosa, Junctional 1b, Severe

Epidermolysis Bullosa, Junctional, Herlitz Type	Epidermolysis Bullosa Letalis
JEB1B	Epidermolysis Bullosa Junctionalis, Herlitz Type
Jeb-Herlitz Type	Herlitz-Pearson-Type Epidermolysis Bullosa
Junctional Epidermolysis Bullosa Herlitz Type	Jeb-H
Junctional Epidermolysis Bullosa Generalisata Gravis	Junctional Epidermolysis Bullosa, Herlitz-Pearson Type
Epidermolysis Bullosa, Junctional, Generalized Severe	Epidermolysis Bullosa, Junctional, Herlitz-Pearson Type
Herlitz Type Epidermolysis Bullosa Junctionalis	Severe Generalized Junctional Epidermolysis Bullosa
Junctional Epidermolysis Bullosa, Herlitz Type	Severe Generalized Jeb
Epidermolysis Letalis	Junctional Epidermolysis Bullosa Gravis
Junctional Epidermolysis Bullosa Herlitz-Pearson Type	Herlitz Disease

Hemolytic Uremic Syndrome, Atypical 1

Atypical Hemolytic-Uremic Syndrome	Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 1
Atypical Hemolytic Uremic Syndrome	Hemolytic Uremic Syndrome, Atypical, Susceptibility To
Ahus	AHUS1
Hemolytic-Uremic Syndrome	Ahus 1
Ahus, Susceptibility To, 1	Hemolytic Uremic Syndrome, Atypical
Non-Shiga-Like Toxin-Associated Hus	Non-Stx-Hus
Nonenteropathic Hus	Atypical Hus
Shiga Toxin-Associated Hemolytic Uremic Syndrome	D+ Hus
Ehec-Hus	Hemolytic Uremic Syndrome Associated With Shiga Toxin-Producing Escherichia Coli
Hemolytic Uremic Syndrome With Diarrhea	Stec-Hus
Shiga-Like Toxin-Associated Hus	Stx-Hus
Typical Hus	Typical Hemolytic Uremic Syndrome
Atypical Hemolytic Uremic Syndrome With Anti-Factor H Antibodies	Atypical Hus With Anti-Factor H Antibodies
Ahus With Anti-Factor H Antibodies	Ahus With Neutralizing Autoantibodies Against Factor H
Hemolytic Uremic Syndrome Atypical 1	Atypical Hemolytic Uremic Syndrome With H Factor Anomaly
D Hus	Hemolytic-Uremic Syndrome Without Diarrhea
Hemolytic-Uremic Syndrome, Atypical, Type 1	Hemolytic Uremic Syndrome, Typical

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS11760	RBMS1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	RBMS1	RGD	RGD:1307777
Mus musculus	RBMS1	MGD	MGI:1861774
Bos taurus	RBMS1	VGNC	VGNC:33809
Felis catus	RBMS1	VGNC	VGNC:69268
Macaca mulatta	RBMS1	VGNC	VGNC:76686
Canis familiaris	RBMS1	VGNC	VGNC:45427

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RBMS1 - RNA binding motif single stranded interacting protein 1 Gene

关于 RBMS1

功能概要

RBMS1 基因产物(2)

RBMS1 蛋白结构

RBMS1 蛋白互作信息

关联疾病

直系同源

热门区域

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RBMS1 - RNA binding motif single stranded interacting protein 1 Gene

关于 RBMS1

功能概要

RBMS1 基因产物(2)

RBMS1 蛋白结构

RBMS1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z