2. Gene
  3. TRMT11 - tRNA methyltransferase 11 homolog Gene

TRMT11 - tRNA methyltransferase 11 homolog Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：tRNA 甲基转移酶 11 同系物

种属: Homo sapiens

同用名: TRM11; MDS024; C6orf75; TRMT11-1

基因 ID: 60487 | 基因类型: protein coding

关于 TRMT11

This gene has 12 transcripts (splice variants) and 213 orthologues. Ubiquitous expression in endometrium (RPKM 2.2), duodenum (RPKM 1.9) and 25 other tissues.

功能概要

预测可启用 tRNA (鸟嘌呤-N2-) -甲基转移酶活性。预测参与 tRNA 甲基化。预计在细胞质中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable tRNA (guanine-N2-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRMT11 基因产物(19)

mRNA Protein Name
NM_001031712.3 NP_001026882.2 tRNA (guanine(10)-N2)-methyltransferase homolog isoform a
NM_001350580.2 NP_001337509.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform b
NM_001350581.2 NP_001337510.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform c
NM_001350582.2 NP_001337511.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform c
NM_001350583.2 NP_001337512.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform c
NM_001350584.2 NP_001337513.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform c
NM_001350585.2 NP_001337514.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform d
NM_001350586.2 NP_001337515.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350587.2 NP_001337516.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350588.2 NP_001337517.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350589.2 NP_001337518.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350590.2 NP_001337519.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350591.2 NP_001337520.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350592.2 NP_001337521.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350593.2 NP_001337522.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350594.2 NP_001337523.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350595.2 NP_001337524.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350596.2 NP_001337525.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
NM_001350597.2 NP_001337526.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform e
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRMT11 蛋白结构

UPF0020

UPF0020: Putative RNA methylase family UPF0020 (190 - 319)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 463 a.a.
蛋白主名 其他名称

tRNA (guanine(10)-N2)-methyltransferase homolog

tRNA guanosine-2'-O-methyltransferase TRM11 homolog

TRMT11 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TRMT11 Q7Z4G4 DCDC2 Homo sapiens Q9UHG0
Y2H Prey Pooling
32296183
种属内
TRMT11 Q7Z4G4 DCDC2 Homo sapiens Q9UHG0
Validated Y2H
32296183
种属内
TRMT11 Q7Z4G4 DCDC2 Homo sapiens Q9UHG0
Y2H Array
32296183
种属内
TRMT11 Q7Z4G4 LHX4 Homo sapiens Q969G2
Y2H Array
32296183
种属内
TRMT11 Q7Z4G4 LHX4 Homo sapiens Q969G2
Y2H Prey Pooling
32296183
种属内
TRMT11 Q7Z4G4 LHX4 Homo sapiens Q969G2
Validated Y2H
32296183
种属内
TRMT11 Q7Z4G4 TRMT112 Homo sapiens Q9UI30
Anti Tag CoIP
34948388
种属内
TRMT11 Q7Z4G4 TRMT112 Homo sapiens Q9UI30
Confocal
34948388
种属内
TRMT11 Q7Z4G4 TRMT112 Homo sapiens Q9UI30
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Combined Oxidative Phosphorylation Deficiency 7

COXPD7

Combined Oxidative Phosphorylation Defect Type 7

Severe C12orf65-Related Combined Oxidative Phosphorylation Defect

Severe C12orf65-Related Coxpd

Combined Oxidative Phosphorylation Deficiency, Type 7
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15089 TRMT11 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TRMT11 VGNC VGNC:47854
Rattus norvegicus TRMT11 RGD RGD:727798
Bos taurus TRMT11 VGNC VGNC:36368
Macaca mulatta TRMT11 VGNC VGNC:79306
Felis catus TRMT11 VGNC VGNC:66568
Mus musculus TRMT11 MGD MGI:1920931
Others TRMT11 NCBI
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