2. Gene
  3. Lif - LIF, interleukin 6 family cytokine Gene

Lif - LIF, interleukin 6 family cytokine Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 60584 | 基因类型: protein coding

关于 Lif

功能概要

Enables Leukemia Inhibitory Factor receptor binding activity. Involved in several processes, including negative regulation of angiogenesis; positive regulation of corticotropin secretion; and transdifferentiation. Located in extracellular space. Biomarker of brain ischemia and congestive heart failure. Orthologous to human LIF (LIF interleukin 6 family cytokine). [provided by Alliance of Genome Resources, Apr 2022]

Lif 基因产物(1)

mRNA Protein Name
NM_022196.3 NP_071532.2 leukemia inhibitory factor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables leukemia inhibitory factor receptor binding IMP
IMP: 通过突变表型推断
14638908 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
16369772 RGD
involved in animal organ regeneration IMP
IMP: 通过突变表型推断
14638908 RGD
involved in astrocyte differentiation IMP
IMP: 通过突变表型推断
17328769 RGD
involved in negative regulation of angiogenesis IDA
IDA: 通过直接分析推断
16643897 RGD
involved in positive regulation of corticotropin secretion IDA
IDA: 通过直接分析推断
20160138 RGD
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
18679704 RGD
involved in retina development in camera-type eye IDA
IDA: 通过直接分析推断
16643897 RGD
involved in transdifferentiation IMP
IMP: 通过突变表型推断
20051627 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
20160138 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leukemia inhibitory factor

cholinergic neuronal differentiation factor

leukemia inhibitory factor (cholinergic differentiation factor)

重组 Lif 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78621 LIF Protein, Rat (HEK293, His) P17777 (S23-F202) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120142 EC359 Inducer 99.09% 否
HY-D0974 Sulforhodamine B sodium salt 99.28% 否
HY-D1603 BODIPY FL-EDA 99.23% 否
HY-RS07640 LIF Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lif NCBI NCBI:3976
Macaca fascicularis Lif NCBI NCBI:102129162
Mus musculus Lif NCBI NCBI:16878
Macaca mulatta Lif NCBI NCBI:715456
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