2. Gene
  3. Lif - leukemia inhibitory factor Gene

Lif - leukemia inhibitory factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 16878 | 基因类型: protein coding

关于 Lif

功能概要

Enables cytokine activity and growth factor activity. Acts upstream of or within several processes, including animal organ development; generation of neurons; and positive regulation of macromolecule metabolic process. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; cranium; early conceptus; and female reproductive system. Orthologous to human LIF (LIF interleukin 6 family cytokine). [provided by Alliance of Genome Resources, Apr 2022]

Lif 基因产物(3)

mRNA Protein Name
NM_001039537.3 NP_001034626.1 leukemia inhibitory factor isoform b
NM_001412335.1 NP_001399264.1 leukemia inhibitory factor isoform a precursor
NM_008501.3 NP_032527.1 leukemia inhibitory factor isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
1522892 MGI
enables growth factor activity IMP
IMP: 通过突变表型推断
1522892 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blood vessel remodeling IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within cell morphogenesis IMP
IMP: 通过突变表型推断
18548006 MGI
acts upstream of cell population proliferation IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within decidualization IDA
IDA: 通过直接分析推断
1522892 MGI
acts upstream of or within decidualization IMP
IMP: 通过突变表型推断
1522892 MGI
acts upstream of or within embryo implantation IDA
IDA: 通过直接分析推断
1522892 MGI
acts upstream of or within embryo implantation IMP
IMP: 通过突变表型推断
1522892 MGI
acts upstream of fibroblast proliferation IMP
IMP: 通过突变表型推断
1522892 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
18548006 MGI
acts upstream of or within lung alveolus development IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within lung development IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within lung lobe morphogenesis IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within lung vasculature development IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within maternal process involved in female pregnancy IMP
IMP: 通过突变表型推断
1522892 MGI
acts upstream of meiotic nuclear division IDA
IDA: 通过直接分析推断
11203703 MGI
acts upstream of or within muscle organ morphogenesis IMP
IMP: 通过突变表型推断
15716414 MGI
acts upstream of or within negative regulation of ERK1 and ERK2 cascade IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within negative regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within negative regulation of meiotic nuclear division IDA
IDA: 通过直接分析推断
11203703 MGI
acts upstream of or within neuron development IGI
IGI: 通过遗传相互作用推断
15716414 MGI
acts upstream of or within positive regulation of astrocyte differentiation IDA
IDA: 通过直接分析推断
10486560 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: 通过突变表型推断
1522892 MGI
acts upstream of or within positive regulation of gene expression IGI
IGI: 通过遗传相互作用推断
7959007 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
21385842 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16691571 MGI
acts upstream of or within regulation of RNA polymerase II regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
21385842 MGI
acts upstream of or within regulation of cell differentiation IGI
IGI: 通过遗传相互作用推断
16258063 MGI
acts upstream of or within response to hypoxia IMP
IMP: 通过突变表型推断
18548006 MGI
acts upstream of or within somatic stem cell population maintenance IDA
IDA: 通过直接分析推断
15358627 MGI
acts upstream of or within somatic stem cell population maintenance IGI
IGI: 通过遗传相互作用推断
15358627 MGI
acts upstream of or within spongiotrophoblast differentiation IGI
IGI: 通过遗传相互作用推断
16258063 MGI
acts upstream of or within stem cell differentiation IDA
IDA: 通过直接分析推断
22949634 MGI
acts upstream of or within trophoblast giant cell differentiation IGI
IGI: 通过遗传相互作用推断
16258063 MGI
acts upstream of or within tyrosine phosphorylation of STAT protein IDA
IDA: 通过直接分析推断
15012602 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leukemia inhibitory factor

d factor

differentiation-stimulating factor

myeloid leukaemia inhibitory factor

重组 Lif 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7084 LIF Protein, Mouse P09056 (S24-F203) ≥95%
HY-P73279 LIF Protein, Mouse (HEK293) P09056/NP_032527.1 (S24-F203) ≥95%
HY-P73280 LIF Protein, Mouse (HEK293, His) P09056 (M1-F203) ≥95%
HY-P78324 LIF Protein, Mouse (HEK293, Fc) P09056 (P25-F203) ≥95%
HY-P700220AF Animal-Free LIF Protein, Mouse (His) P09056 (S24-F203) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990461 Anti-LIF Antibody (MSC-1) Inhibitor 98.51% Phase 1
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120142 EC359 Inducer 99.09% 否
HY-D0974 Sulforhodamine B sodium salt 99.28% 否
HY-100949 EC330 99.60% 否
HY-D1603 BODIPY FL-EDA 99.23% 否
HY-RS07640 LIF Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lif NCBI NCBI:3976
Macaca fascicularis Lif NCBI NCBI:102129162
Rattus norvegicus Lif NCBI NCBI:60584
Macaca mulatta Lif NCBI NCBI:715456
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