1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Neurotrophic Factors
  4. Leukemia Inhibitory Factor
  5. LIF 蛋白, Mouse (HEK293, His)

LIF 蛋白, Mouse (HEK293, His)

目录号: HY-P73280
产品使用指南

LIF(白血病抑制因子)促进白血病细胞的终末分化,诱导造血细胞和神经元细胞分化。它还刺激肝细胞中的急性期蛋白质合成。LIF 的多方面作用强调了其在调节造血、神经发生和肝脏反应中的重要性。LIF 蛋白, Mouse (HEK293, His) 是重组的 LIF 蛋白,由 HEK293 表达,带有 C-His 标签。

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描述

LIF (Leukemia Inhibitory Factor) prompts terminal differentiation in leukemic cells, inducing hematopoietic and neuronal cell differentiation.It also stimulates acute-phase protein synthesis in hepatocytes.LIF's multifaceted role underscores its significance in regulating hematopoiesis, neurogenesis, and hepatic responses.LIF Protein, Mouse (HEK293, His) is the recombinant mouse-derived LIF protein, expressed by HEK293 , with C-His labeled tag.

研究背景

LIF(白血病抑制因子)具有促进白血病细胞终末分化的能力,具有多种活性。值得注意的是,它诱导正常细胞和髓性白血病细胞的造血分化,促进神经元细胞分化,并刺激肝细胞中急性期蛋白的合成。这种多方面的作用强调了 LIF 在协调各种细胞过程中的重要性,有助于调节造血、神经发生和肝脏反应。

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

P09056 (M1-F203)

基因 ID
蛋白结构
N-term
LIF (M1-F203)
Accession # P09056
His
C-term
同用名
LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI
分子量

35-45 kDa

纯度

Greater than 85% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

LIF Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
LIF Protein, Mouse (HEK293, His)
目录号:
HY-P73280
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