RPL6 - ribosomal protein L6 Gene

中文名称：核糖体蛋白 L6

种属: Homo sapiens

同用名: L6; TXREB1; SHUJUN-2; TAXREB107

基因 ID: 6128 | 基因类型: protein coding

关于 RPL6

Cytogenetic location: 12q24.13 Genomic coordinates (GRCh38): 12:112,405,181-112,418,835 (from NCBI)

This gene has 13 transcripts (splice variants) and 333 orthologues. Ubiquitous expression in ovary (RPKM 360.8), lymph node (RPKM 224.8) and 25 other tissues.

功能概要

该基因编码 60S 核糖体亚基的蛋白质成分。该蛋白可特异性结合人 T 细胞白血病病毒 1 型的税收反应增强子元件的结构域 C，并可能参与税收介导的转录反式激活。对于编码核糖体蛋白的基因来说，这是典型的，该基因有多个经过处理的假基因分散在整个基因组中。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 2 月]

This gene encodes a protein component of the 60S ribosomal subunit. This protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

RPL6 基因产物(8)

mRNA	Protein	Name
NM_000970.6	NP_000961.2	60S ribosomal protein L6 isoform 1
NM_001024662.3	NP_001019833.1	60S ribosomal protein L6 isoform 1
NM_001320137.2	NP_001307066.1	60S ribosomal protein L6 isoform 1
NM_001320138.2	NP_001307067.1	60S ribosomal protein L6 isoform 1
NM_001320139.2	NP_001307068.1	60S ribosomal protein L6 isoform 1
NM_001320140.2	NP_001307069.1	60S ribosomal protein L6 isoform 1
NM_001320141.2	NP_001307070.1	60S ribosomal protein L6 isoform 1
NM_001320142.1	NP_001307071.1	60S ribosomal protein L6 isoform 2

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	14743216	GOA
enables structural constituent of ribosome	IDA IDA: 通过直接分析推断	23636399	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in cytoplasmic translation	IDA IDA: 通过直接分析推断	25957688	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasmic ribonucleoprotein granule	IDA IDA: 通过直接分析推断	15121898	GOA
part of cytosolic large ribosomal subunit	IDA IDA: 通过直接分析推断	25957688	GOA
part of cytosolic large ribosomal subunit	IPI IPI: 通过物理相互作用推断	25901680	GOA
located in cytosolic ribosome	IDA IDA: 通过直接分析推断	23636399	GOA
located in nucleus	IDA IDA: 通过直接分析推断	25468996	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RPL6 蛋白结构

Ribosomal_L6e_N

Ribosomal_L6e

0
100
200
288 a.a.

蛋白主名

其他名称

60S ribosomal protein L6

DNA-binding protein TAXREB107

RPL6 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RPL6	Q02878	MAP3K14	Homo sapiens	Q99558	TAP	14743216

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Human T-Cell Leukemia Virus Type 1

Htlv-1

Human T Lymphotropic Virus Type 1

T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia	Acute T Cell Leukemia
Precursor T Lymphoblastic Leukemia	Precursor T-Lymphoblastic Lymphoma/Leukemia
T Acute Lymphoblastic Leukemia	T-Cell Acute Lymphocytic Leukaemia
T-Cell Lymphoblastic Leukemia/Lymphoma	Leukemia T-Cell
Leukemia, T-Cell	Leukemia, Acute, Lymphoblastic, T-Cell
Leukemia, T-Cell Acute Lymphoblastic	Leukemia, Acute T-Cell
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Precursor T-Cell Lymphoblastic Lymphoma
Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Shwachman-Diamond Syndrome 1

Shwachman-Diamond Syndrome	Shwachman Syndrome
Shwachman-Bodian-Diamond Syndrome	Sds
Pancreatic Insufficiency And Bone Marrow Dysfunction	Shwachman-Bodian Syndrome
SDS1	Lipomatosis Of Pancreas, Congenital
Congenital Lipomatosis Of Pancreas	Shwachman-Diamond Type Metaphyseal Dysplasia
Metaphyseal Chondrodysplasia, Shwachman Type	Shwachman-Diamond-Oski Syndrome

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia	Aase Syndrome
Erythrogenesis Imperfecta	Anemia, Diamond-Blackfan
Congenital Hypoplastic Anemia	Aase-Smith Ii Syndrome
Bds	Blackfan-Diamond Anemia
Congenital Prca	Congenital Hypoplastic Anemia, Blackfan-Diamond Type
Dba	Blackfan - Diamond Syndrome
Chronic Constitutional Pure Red Cell Anaemia	Anemia Diamond Blackfan Type
Anemia Congenital Erythroid Hypoplastic	Aregenerative Anemia Chronic Congenital
Blackfan Diamond Syndrome	Red Cell Aplasia, Pure Hereditary
Aase-Smith Syndrome Ii	Bda
Blackfan Diamond Anemia	Blackfan-Diamond Disease
Blackfan-Diamond Syndrome	Chronic Congenital Agenerative Anemia
Congenital Erythroid Hypoplastic Anemia	Congenital Hypoplastic Anemia Of Blackfan And Diamond
Congenital Pure Red Cell Anemia	Hypoplastic Congenital Anemia
Inherited Erythroblastopenia	Pure Hereditary Red Cell Aplasia
Anemia, Hypoplastic, Congenital	Anemia Hypoplastic Congenital
Fanconi Anemia	Constitutional Aplastic Anemia
Diamond-Blackfan Anemia 1	Aase Smith Syndrome 2
Congenital Red Cell Aplasia	Red Cell Aplasia Of Infants
Pure Red Cell Aplasia Of Infants	Congenital Red Cell Aplastic Anaemia
Congenital Pure Red Cell Anaemia	Congenital Erythroid Hypoplasia
Pearson Marrow-Pancreas Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

目录号	产品名	作用方式	纯度	Phase
HY-129239	Farudodstat		99.68%	Phase 2

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12202	RPL6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	RPL6	RGD	RGD:619826
Felis catus	RPL6	VGNC	VGNC:80480
Mus musculus	RPL6	MGD	MGI:108057

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RPL6 - ribosomal protein L6 Gene

关于 RPL6

功能概要

RPL6 基因产物(8)

RPL6 蛋白结构

RPL6 蛋白互作信息

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

RPL6 - ribosomal protein L6 Gene

关于 RPL6

功能概要

RPL6 基因产物(8)

RPL6 蛋白结构

RPL6 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z