RPL34 - ribosomal protein L34 Gene

中文名称：核糖体蛋白 L34

种属: Homo sapiens

同用名: L34

关于 RPL34

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 60S 亚基的一个组成部分。该蛋白属于核糖体蛋白 L34E 家族。它位于细胞质中。该基因原先被认为位于 17q21，后来被映射到 4q。已在一些癌细胞中观察到该基因的过度表达。可变剪接导致多个转录变体，所有变体都编码相同的亚型。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供，2016 年 2 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Overexpression of this gene has been observed in some Cancer cells. Alternative splicing results in multiple transcript variants, all encoding the same isoform. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Feb 2016]