1. Gene
  2. RPS13 - ribosomal protein S13 Gene

RPS13 - ribosomal protein S13 Gene

中文名称:核糖体蛋白 S13

种属: Homo sapiens

同用名: S13

基因 ID: 6207 | 基因类型: protein coding

关于 RPS13

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:17,074,388-17,077,667 (from NCBI)

This gene has 10 transcripts (splice variants) and 211 orthologues. Ubiquitous expression in ovary (RPKM 892.5), lymph node (RPKM 558.5) and 25 other tissues.

功能概要

核糖体是催化蛋白质合成的细胞器,由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 40S 亚基的一个组成部分。该蛋白属于核糖体蛋白 S15P 家族。它位于细胞质中。该蛋白已被证明与大鼠的 5.8S rRNA 结合。大肠杆菌直系同源物 (核糖体蛋白 S15) 的基因产物在核糖体组装的早期阶段起作用。该基因与位于其第三和第五个内含子中的两个 U14 小核仁 RNA 基因共转录。作为典型的编码核糖体蛋白的基因,该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供,2008 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S15P family of ribosomal proteins. It is located in the cytoplasm. The protein has been shown to bind to the 5.8S rRNA in rat. The gene product of the E. coli ortholog (ribosomal protein S15) functions at early steps in ribosome assembly. This gene is co-transcribed with two U14 small nucleolar RNA genes, which are located in its third and fifth introns. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPS13 基因产物(1)

mRNA Protein Name
NM_001017.3 NP_001008.1 40S ribosomal protein S13

RPS13 蛋白结构

Ribosomal_S13_N

Ribosomal_S13_N: Ribosomal S13/S15 N-terminal domain (1 - 60)

Ribosomal_S15

Ribosomal_S15: Ribosomal protein S15 (66 - 150)

  • 0
  • 100
  • 151 a.a.
蛋白主名 其他名称

40S ribosomal protein S13

small ribosomal subunit protein uS15

重组 RPS13 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71683 RPS13 Protein, Human (GST) P62277 (R3-A151) ≥95%

关联疾病

疾病名称 别名
Osgood-Schlatter'S Disease

Osgood-Schlatter Disease

Juvenile Osteochondrosis Of Tibial Tubercle

Osteochondrosis

Osteochondritis Of Tibial Tubercle

Osteochondrosis Of Proximal Tibia

Aseptic Necrosis Of The Tibial Tubercle

Osteochondrosis Of The Tibial Tubercle

Osteochondritis Juvenilis

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RPS13 RGD RGD:621027
Macaca mulatta RPS13 VGNC VGNC:107637
Mus musculus RPS13 MGD MGI:1915302
Others RPS13 NCBI