2. Gene
  3. TSPAN31 - tetraspanin 31 Gene

TSPAN31 - tetraspanin 31 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：四跨膜蛋白 31

种属: Homo sapiens

同用名: SAS

基因 ID: 6302 | 基因类型: protein coding

关于 TSPAN31

Cytogenetic location: 12q14.1 Genomic coordinates (GRCh38): 12:57,745,039-57,750,219 (from NCBI)

This gene has 14 transcripts (splice variants), 201 orthologues and 32 paralogues. Ubiquitous expression in thyroid (RPKM 18.9), adrenal (RPKM 13.0) and 25 other tissues.

功能概要

由该基因编码的蛋白质是跨膜 4 超家族的成员，也称为四跨膜蛋白家族。这些成员中的大多数是细胞表面蛋白，其特征在于存在四个疏水结构域。这些蛋白质介导在细胞发育、活化、生长和运动的调节中起作用的信号转导事件。这种编码的蛋白质被认为参与了与生长相关的细胞过程。该基因与肿瘤发生和骨肉瘤有关。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]

TSPAN31 基因产物(3)

mRNA Protein Name
NM_001330168.2 NP_001317097.1 tetraspanin-31 isoform 2
NM_001330169.2 NP_001317098.1 tetraspanin-31 isoform 3 precursor
NM_005981.5 NP_005972.1 tetraspanin-31 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TSPAN31 蛋白结构

Tetraspannin

Tetraspannin: Tetraspanin family (8 - 194)

  • 0
  • 100
  • 210 a.a.
蛋白主名 其他名称

tetraspanin-31

sarcoma-amplified sequence

TSPAN31 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TSPAN31 Q12999 CMTM5 Homo sapiens Q96DZ9-2
Validated Y2H
32296183
种属内
TSPAN31 Q12999 NAT8 Homo sapiens Q9UHE5
Validated Y2H
32296183
种属内
TSPAN31 Q12999 SLC30A2 Homo sapiens Q9BRI3
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 TSPAN31 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76686 TSPAN31 Protein, Human (HEK293, Fc) Q12999 (C94-K173) ≥95%

关联疾病

疾病名称 别名
Breast Liposarcoma

Liposarcoma Of The Breast
Childhood Liposarcoma

Pediatric Liposarcoma
Well-Differentiated Liposarcoma

Atypical Lipomatous Tumor

Atypical Lipoma

Alt

Wdls

Liposarcoma, Well Differentiated

Pleomorphic Lipoma
Soft Tissue Chondroma

Extraskeletal Chondroma
Liposarcoma

Lipomatous Cancer
Sarcoma

Connective And Soft Tissue Neoplasm

Tumor Of Soft Tissue And Skeleton

Sarcomas

Sarcoma - Category
Pleomorphic Liposarcoma

Pls

Liposarcoma Pleomorphic

Liposarcoma, Pleomorphic
Diffuse Lipomatosis
Embryonal Rhabdomyosarcoma

Rhabdomyosarcoma, Embryonal

Rhabdomyosarcoma Embryonal

Botryoid Rhabdomyosarcoma

Erms

Spindle Cell Rhabdomyosarcomas
Retroperitoneal Sarcoma
Dedifferentiated Liposarcoma

Ddls

Liposarcoma Dedifferentiated

Liposarcoma, Dedifferentiated
Peripheral Osteosarcoma

Surface Osteosarcoma

Bone Surface Osteosarcoma
Cellular Myxoid Liposarcoma

Round Cell Liposarcoma
Anaplastic Astrocytoma

Grade Iii Astrocytoma

Astrocytoma, Anaplastic

Grade Iii Astrocytic Tumor
Lipomatosis, Multiple

Lipoma

Familial Multiple Lipomatosis

Lipomatosis, Familial Multiple

Benign Lipomatous Tumor

Lipomatous Neoplasm

Multiple Lipomatosis

Fml

Lipo

Benign Tumor Of Adipose Tissue

Lipomatous Tumor

Tumor Of Adipose Tissue

Neoplasms, Adipose Tissue

Lipomas
Familial Retinoblastoma

Hereditary Retinoblastoma

Retinoblastoma
Myxoid Liposarcoma

Myxoid/Round Cell Liposarcoma

Liposarcoma, Myxoid

Mrcls

Myxoliposarcoma

MXLIPO

Liposarcoma Myxoid

Liposarcoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15167 TSPAN31 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus TSPAN31 MGD MGI:1914375
Bos taurus TSPAN31 VGNC VGNC:36437
Canis familiaris TSPAN31 VGNC VGNC:47920
Macaca mulatta TSPAN31 VGNC VGNC:78552
Rattus norvegicus TSPAN31 RGD RGD:1309876
Felis catus TSPAN31 VGNC VGNC:66631
Others TSPAN31 NCBI
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