2. Gene
  3. Ccn2 - cellular communication network factor 2 Gene

Ccn2 - cellular communication network factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ctgf; CTGRP

基因 ID: 64032 | 基因类型: protein coding

关于 Ccn2

功能概要

Enables fibronectin binding activity and growth factor activity. Involved in several processes, including positive regulation of G0 to G1 transition; positive regulation of collagen biosynthetic process; and positive regulation of macromolecule metabolic process. Located in several cellular components, including cell cortex; cis-Golgi network; and perinuclear region of cytoplasm. Used to study endomyocardial fibrosis. Biomarker of several diseases, including artery disease (multiple); lung disease (multiple); membranoproliferative glomerulonephritis; primary biliary cholangitis; and restrictive cardiomyopathy (multiple). Orthologous to human CCN2 (cellular communication network factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ccn2 基因产物(1)

mRNA Protein Name
NM_022266.2 NP_071602.1 CCN family member 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fibronectin binding IDA
IDA: 通过直接分析推断
18167060 RGD
enables growth factor activity IDA
IDA: 通过直接分析推断
10026205 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium ion transmembrane import into cytosol IMP
IMP: 通过突变表型推断
19707545 RGD
involved in cellular response to fatty acid IEP
IEP: 通过表达模式推断
19625611 RGD
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
19625611 RGD
involved in cellular response to interleukin-13 IEP
IEP: 通过表达模式推断
21804025 RGD
involved in extracellular matrix constituent secretion IMP
IMP: 通过突变表型推断
18613219 RGD
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
12193543 RGD
involved in lung development IEP
IEP: 通过表达模式推断
19361631 RGD
involved in microtubule depolymerization IMP
IMP: 通过突变表型推断
20858895 RGD
involved in positive regulation of G0 to G1 transition IMP
IMP: 通过突变表型推断
18613219 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
19625611 RGD
involved in positive regulation of cardiac muscle contraction IMP
IMP: 通过突变表型推断
19707545 RGD
involved in positive regulation of cell activation IMP
IMP: 通过突变表型推断
18613219 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
19570811 RGD
involved in positive regulation of collagen biosynthetic process IMP
IMP: 通过突变表型推断
19570811 RGD
involved in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: 通过突变表型推断
19625611 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
19570811 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
19707545 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
17250813 RGD
involved in response to anoxia IEP
IEP: 通过表达模式推断
18929865 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
19509476 RGD
involved in response to fatty acid IEP
IEP: 通过表达模式推断
19656915 RGD
involved in response to mineralocorticoid IEP
IEP: 通过表达模式推断
19521108 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
19558898 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
19667256 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell cortex IDA
IDA: 通过直接分析推断
19359517 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
19570811 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
19359517 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CCN family member 2

connective tissue growth factor

connective tissue growth-related protein

重组 Ccn2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P79369 CCN2/CTGF Protein, Rat (HEK293) Q9R1E9 (Q25-A347) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P5314 OK2 Inhibitor 95.95% 否
HY-RS02111 CCN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccn2 NCBI NCBI:1490
Mus musculus Ccn2 NCBI NCBI:14219
Macaca mulatta Ccn2 NCBI NCBI:714520
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z