2. Gene
  3. SRSF4 - serine and arginine rich splicing factor 4 Gene

SRSF4 - serine and arginine rich splicing factor 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：富丝氨酸和精氨酸的剪接因子 4

种属: Homo sapiens

同用名: SFRS4; SRP75

基因 ID: 6429 | 基因类型: protein coding

关于 SRSF4

Cytogenetic location: 1p35.3 Genomic coordinates (GRCh38): 1:29,147,743-29,181,900 (from NCBI)

This gene has 8 transcripts (splice variants), 239 orthologues and 8 paralogues. Ubiquitous expression in placenta (RPKM 33.0), bone marrow (RPKM 32.4) and 25 other tissues.

功能概要

该基因编码富含精氨酸/丝氨酸的剪接因子家族的成员。编码的蛋白质可能在 mRNA 加工中起作用。[RefSeq 提供，2009 年 2 月]

This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq, Feb 2009]

SRSF4 基因产物(1)

mRNA Protein Name
NM_005626.5 NP_005617.2 serine/arginine-rich splicing factor 4

SRSF4 蛋白结构

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (4 - 64)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (106 - 171)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 494 a.a.
蛋白主名 其他名称

serine/arginine-rich splicing factor 4

SR splicing factor 4

SRSF4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SRSF4 Q08170 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
Intra SRSF4 Q08170 UBE2I Homo sapiens Q7KZS0
Validated Y2H
32296183
Intra SRSF4 Q08170 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
Intra SRSF4 Q08170 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
Intra SRSF4 Q08170 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
Intra SRSF4 Q08170 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
Intra SRSF4 Q08170 TRA2B Homo sapiens P62995
Y2H Prey Pooling
32296183
Intra SRSF4 Q08170 TRA2B Homo sapiens P62995
Y2H Array
32296183
Intra SRSF4 Q08170 SRSF6 Homo sapiens Q13247
Y2H Pooling
16189514
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Frontotemporal Dementia

Pallidopontonigral Degeneration

Frontotemporal Lobar Degeneration

Semantic Dementia

FTD

Frontotemporal Lobe Dementia

Multiple System Tauopathy With Presenile Dementia

Dementia, Frontotemporal

Frontotemporal Dementia With Parkinsonism

Mstd

Frontotemporal Lobar Degeneration With Tau Inclusions

Ftld With Tau Inclusions

Dementia, Frontotemporal, With Parkinsonism

Fldem

Ftdp17

Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex

Ddpac

Wilhelmsen-Lynch Disease

Wld

Ppnd

Dementia, Frontotemporal, With Or Without Parkinsonism

Semantic Primary Progressive Aphasia

Semantic Variant Ppa

Wilhemsen-Lynch Disease

Frontotemporal Dementia-Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17

Ftd-Als

Ftld

Pick Complex

Pick Disease Of The Brain

Frontotemporal Dementia With Parkinsonism-17

Grn-Related Frontotemporal Dementia

Frontotemporal Dementia With Motor Neuron Disease

Dementia In Fronto-Temporal Lobar Degeneration

Ftd - [Frontotemporal Dementia]

Temple Dementia

Frontal Lobe Dementia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13795 SRSF4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SRSF4 VGNC VGNC:46820
Mus musculus SRSF4 MGD MGI:1890577
Bos taurus SRSF4 VGNC VGNC:35302
Rattus norvegicus SRSF4 RGD RGD:1561347
Macaca mulatta SRSF4 VGNC VGNC:100150
Felis catus SRSF4 VGNC VGNC:65696
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